In: Biology
If the a and b loci are 20 cM apart and an AA BB individual and an aa bb individual mate: What gametes will the F1 individuals produce, and in what proportions? What phenotypic classes in what proportions are expected in the F2 generation (assuming complete dominance for both genes) (show procedure, NO score for direct result)?
Mating of AABB X aabb
F1 generation AaBb
gamete of AaBb -----------------> AB, ab , Ab and aB
A total number of gametes is four, from which Ab and ab are
non-recombinant, while Ab, an aB are recombinant.
The distance between these two loci is 20 cM, which tells us that
there is a 20percent probability for these genes to be inherited
together. We can conclude that the rest 80 percent would be
non-recombinant heritage pattern.
Since the probability is the same for all the gametes, the
percentage is 40 % for AB and 40 %for ab and 10% for Ab as well as
10% for aB of the non-recombinant alleles.
PROPORTION OF F2 generation
GAMETES | AB (40%) | ab (40%) | Ab (10%) | aB (10%) |
AB(40%) | AABB 16% | AaBb 16% | AABb 4% | AaBB 4% |
ab(40%) | AaBb 16% | aabb 16% | Aabb 4% | aaBb 4% |
Ab (10%) | AABb 4% | Aabb 4% | AAbb 1% | AaBb 1% |
aB (10%) | AaBB 4% | aaBb 4% | AaBb 1% | aaBB 1% |
Summary of phenotypes:
A and B 66%
A and b 9%
a and B 9%
a and b 16%