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In: Nursing

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

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Expert Solution

SYSTEMIC LUPUS ERYTHEMATOSUS is also called as LUPUS .

Lupus is a autoimmune disease,were the immune system attacks the body's own tissue which leads to inflammation and tissue damage.The disease can effect any part of the body, but commonly seen in heart,joints, skin ,lungs ,blood vessels,liver, kidney and nervous system.

ETIOLOGY: Etiology is currently unknown but there are several factors involved in it.

SIGNS AND SYMPTOMS:

  • Arthralgia 95%
  • Fever more than 100 degree 90%
  • Arthritis 90%
  • Prolonged fatigue 81%
  • Skin rashes 74%
  • Anemia 71%
  • Kidney involvement 50%
  • Pleurisy 45%
  • Butterfly shaped rash across the cheeks and nose 42%
  • Photosensitivity 30%
  • Alopecia 27%
  • Abnormal blood clotting 20%
  • Fingers turn to white or blue in cold 17%
  • Mouth or nose ulcer 12%

LAB AND OTHER STUDIES:

Complete blood count,ESR,Comprehensive metabolic panel,creatine phosphokinase,urinalysis,serologies,renal biopsy

PROGNOSIS

Usually chronic, relapsingand unpreditable,remission may last for years.If initial acute phase is controlled, even if very severe long term prognosis is good.Most severe conditionds require more toxic therapies, which increase risk of mortality.

TREATMENT

Drugs with least side effect,lowest dose to control disease,long term damage preventions.

Mild disease avoid steriods .

severe cases aggressive treatment.

NSAIDs-ACETAMINOPHEN

CORTICOSTEROIDS-PREDNISONE

ANTI-MALARIAL-HYDROXYCHLOROQUINE


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