The bacterium Helicobacter pylori colonizes the
stomachs of > 50% of the world's population. This species is
what some call a "pathobiont," an organism that is a member of the
human microbiome but can cause disease in some individuals. Of
those infected with H. pylori, approximately 5%
develop gastric ulcers and 1-3% develop gastric cancer.
Interestingly, hosts that are colonized with H. pylori are
also less likely to develop allergic diseases and active
tuberculosis!
The high rate of gastric cancer...
Sinclair Pharmaceuticals, a small drug company, develops a
vaccine that will protect against Helicobacter pylori,a bacteria
that is the cause of a number of diseases of the stomach. It is
expected that Sinclair Pharmaceuticals will experience extremely
high growth over the next three years and will reinvest all of its
earnings in expanding the company over this time. Earnings were $
1.25 per share before the development of the vaccine and are
expected to grow by 40% per year for...
Twocombinationdrugtherapies(TreatmentAandTreatmentB)have been
developed for eradicating Helicobacter pylori in human
patients. The effectiveness of these treatments depends on whether
or not the patient is resistant to the chemical compound
Metronidazole, but apatient’s resistance status is not routinely
determined before beginningtreatment. Treatment A successfully
eradicates Helicobacter pylori in 92% of resistant
patients and 87% of non-resistant patients. The corresponding
proportions for Treatment B are 75% and 95%.
(i) Denote by θ (0 < θ < 1) the proportion of the affected
population...
QUESTION 6
Helicobacter pylori causes:
Toxic shock syndrome.
Stomach ulcers.
Stomach cancers.
Both b and c.
7. Which Escherichia coli strain causes gastroenteritis?
EPEC.
ETEC.
EIEC.
All of the above.
8. A subunit vaccine contains:
The protein.
The nucleic acid.
The entire virus.
Both a and b.
9.
In the complement-fixation test, a red color means:
Positive test.
Negative test.
Invalid test.
Both b and c.
10. An anti-human IgG antibody is an antibody that binds to
human IgG antibody....
Which statement is false concerning H. pylori . Mark all
that apply
a. Gastritis arises due to mucosal cell destruction and
a proinflammatory response
b. It is a carcinogenic bacterium that can lead to
gastric cancer with prolonged exposure
c. Bleeding peptic ulcers may occur in approximately 15%
of the population
d. H. pylori can not be treated with antibiotic
drugs
H. pylori exclusively colonized the small intestines in
people
Treatment of mycobacterial infections generally entails a four-
to nine-month antibiotic regimen. How is the length of treatment
connected to the fact that mycobacterial species tend to grow very
slowly?