A 30-year-old woman is taking ibuprofen for severe dysmenorrhea but develops epigastric pain. You prescribe a...

A 30-year-old woman is taking ibuprofen for severe dysmenorrhea but develops epigastric pain. You prescribe a medication to prevent gastritis. Which of the following best describes the medication?

Group of answer choices

PGI2 analog

PGE1 antagonist

PGI2 antagonist

PGE2 antagonist

PGE1 analog

PGE2 analog

Solutions

Expert Solution

A 30-year-old woman is taking ibuprofen for severe dysmenorrhea but develops epigastric pain. You prescribe a medication to prevent gastritis. Which of the following best describes the medication?

NSAID causes gastric ulcer and bleeding, it blocks Cox-1 enzyme and disrupting the production of prostaglandins in the stomach. NSAID are best known are prostaglandins antagonist. PGE1, PGE2 and PGI are prostaglandin. Prostaglandin analog are used in the treatment of gastritis with H2 receptor antagonist

ANS-

For any multiple type question use a method of elimination and knowledge of treatment plan for gastritis

Options b (PGE1 antagonist), c (PGI2 antagonist), and d (PGE2 antagonist) are incorrect, 3 of the are antagonist of prostaglandins and these may exaggerate the conditions.

PGI2 analog these analogs are used in the treatment of the pulmonary arterial hypertension; it acts an effective vasodilator and relief the symptoms hence this option is incorrect.

PGE1 analog is used in the treatment of the duodenal ulcer example misoprostol which is a synthetic prostaglandin E1. It prevents gastric ulcer in the patient taking NSAID (ibrufin) hence this option is correct.

PGE2 analog is used in the induction of labor, bleeding after delivery and termination of pregnancy. This option is incorrect.

FOR ANY DOUBT POST A QUESTION IT WILL BE HIGHLY APPRECIATED.

Nightingale answered 2 years ago

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