Question

In: Biology

Suppose when you count the actual number of offspring produced and determine their genotypes, you get...

Suppose when you count the actual number of offspring produced and determine their genotypes, you get the following: 469 AA, 448 Aa and 83 aa. What are the allele frequencies for these individuals in this generation?

frequency of dominant allele _____.

frequency of recessive allele ______.

YES OR NO - Is this population in Hardy-Weinberg equilibrium (pick one)

Simply and briefly - explain why ________

Solutions

Expert Solution

frequency of dominant allele 0.69.

frequency of recessive allele 0.31.

YES OR NO - Is this population in Hardy-Weinberg equilibrium (pick one): YES

Simply and briefly - explain why FIND THE BELOW CALCULATION

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The steps involved here

Step 1: Calculation number of alleles

Genotype

Freequency

Allele A

Allele a

Total

AA

469

938

0

938

Aa

448

448

448

896

aa

83

0

166

166

Total

1000

1386

614

2000

Step 2: Calculation of allele frequencies

Frequency = No of a alleles/Total no of alleles

Allele A (Dominant allele)

= 1386/2000

= 0.69

Allele a (Recessive allele)

= 614/2000

= 0.31

Step 3: Expected genotype frequencies estimation

Genotype

Genotype frequencies

For 1000 population the freqeunecies

AA

= 0.69*0.69= 0.480

*1000

=480

Aa

2*0.69*0.31= 0.426

*1000

=426

aa

0.31*0.31= 0.094

*1000

=94

Step 4: Chi-square test

Null hypothesis: The observed values are not deviating from the expected values.

Category

AA

Aa

aa

Observed values

469

448

83

Exprected Values

480

426

94

Deviation

-11

22

-11

D^2

126.54

506.16

126.54

D^2/E

0.26

1.19

1.34

2.80

X^2

2.80

Degrees of freedom

1

Inference: The calculated chisquar value i.e. 2.80 is less than the table value i.e.3.84 at 1 DF and 0.05 probability, hence the null hypothesis is accepted, which means the population is in HW equilibrium.


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