In: Biology
Suppose when you count the actual number of offspring produced and determine their genotypes, you get the following: 469 AA, 448 Aa and 83 aa. What are the allele frequencies for these individuals in this generation?
frequency of dominant allele _____.
frequency of recessive allele ______.
YES OR NO - Is this population in Hardy-Weinberg equilibrium (pick one)
Simply and briefly - explain why ________
frequency of dominant allele 0.69.
frequency of recessive allele 0.31.
YES OR NO - Is this population in Hardy-Weinberg equilibrium (pick one): YES
Simply and briefly - explain why FIND THE BELOW CALCULATION
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The steps involved here
Step 1: Calculation number of alleles
Genotype |
Freequency |
Allele A |
Allele a |
Total |
AA |
469 |
938 |
0 |
938 |
Aa |
448 |
448 |
448 |
896 |
aa |
83 |
0 |
166 |
166 |
Total |
1000 |
1386 |
614 |
2000 |
Step 2: Calculation of allele frequencies
Frequency = No of a alleles/Total no of alleles
Allele A (Dominant allele) |
= 1386/2000 |
= 0.69 |
Allele a (Recessive allele) |
= 614/2000 |
= 0.31 |
Step 3: Expected genotype frequencies estimation
Genotype |
Genotype frequencies |
For 1000 population the freqeunecies |
|
AA |
= 0.69*0.69= 0.480 |
*1000 |
=480 |
Aa |
2*0.69*0.31= 0.426 |
*1000 |
=426 |
aa |
0.31*0.31= 0.094 |
*1000 |
=94 |
Step 4: Chi-square test
Null hypothesis: The observed values are not deviating from the expected values.
Category |
AA |
Aa |
aa |
|
Observed values |
469 |
448 |
83 |
|
Exprected Values |
480 |
426 |
94 |
|
Deviation |
-11 |
22 |
-11 |
|
D^2 |
126.54 |
506.16 |
126.54 |
|
D^2/E |
0.26 |
1.19 |
1.34 |
2.80 |
X^2 |
2.80 |
|||
Degrees of freedom |
1 |
Inference: The calculated chisquar value i.e. 2.80 is less than the table value i.e.3.84 at 1 DF and 0.05 probability, hence the null hypothesis is accepted, which means the population is in HW equilibrium.