In: Biology
11. Loss of heterozygosity enhances progression to carcinoma by increasing the rate of driver mutations in cancer cells. A) True B) False
12. The large increases in cancer incidence observed with certain types cancer in immune compromised individuals indicates that human tumor cells highly immunogenic. A) True B) False
13. Loss of VHL in renal cancer prevents the hydroxylation of HIF and thusly stabilizes HIF resulting in the induction of angiogenesis and the expression of glycolytic genes. A) True B) False
Tumor cells produce high levels of PD-1 to absorb PD-L1 produced by immune cells.
A) True
B) False