Question

Discuss the hormonal regulation of the mammalian menstrual cycle. Specifically discuss the interrelationships of the specific hormones of the arcuate nucleus, pituitary gonadotropes, ovarian follicular theca and granulosa cells and finally the corpus luteum. Please include a discussion of the role of the gonadotropin-releasing hormone.

Answer 1

Ans)the ovarian cycle are controlled by chemical messengers and hormones.Leutenizing hormone and Follicle stimulating hormone produced by anterior pitutary gland promote ovulation and stimulate the ovaries to produce estrogen and progesterone.

Gonadotropin releasing hormone(GnRH) is secreted by hypothalamus and stimulates the release of Follicle releasing hormone (FSH) and leutanizing hormone (LH) from anterior pitutary hormone . FSH initiates follicular growth and secretion of estrogen by the growth follicles.LH stimulates the further development of the ovarian follicles and full secretion of estrogens brings out ovulation , promotes fornation of corpus luteum and stimulates the production of estrogens and progesterone,relaxin and inhibin by the corpys luteum.

Estrogen are hormone that promote the development and maintenance of female reproductive structures, secondary sex characteristics and the breasts.moderate amount of estrogen in the body inhibit both the release of growth hormone releasing hormone and LH and FSH by anterior pitutary gland.

Inhibin is secreted by granulosa cell of growing follicles and by corpus luteum of the ovary .It inhibit secretion of FSH and to a lesser extent LH.