Question 1
Correct answer - C
Explanation
- Onset of action of a drug depended upon its rate of absorption
into the blood vessels and also depends upon the intrinsic
properties of the drug.
 
- When a drug is given i.v. it directly enters the blood.
 
- Therefore, it has a rapid onset of action.
 
Incorrect options
a) Precise control of the dosage is one of the important reason
why an intravenous mode may be chosen over an oral route
- In the case of oral medication, the drug enters the alimentary
tract.
 
- From there it is absorbed into the circulation.
 
- From the gut, it enters the liver, where the first past
metabolism takes place.
 
- This reduces the blood levels of the drug.
 
- As a result, final drug level is unpredictable.
 
- This problem doesn't occur with the intravenous route.
 
b) inability of the person to take medication orally
- This is an important reason to receive drugs
intravenously.
 
- Some patients may be extremely breathless or may have excessive
vomiting.
 
- Such a patient will not be able to consume medicine
orally.
 
- The intravenous route is preferred in such patients.
 
- Once the patient is able to tolerate oral feeds, oral
medications can be started
 
d) Inability to be absorbed when given orally
- Some drugs cannot be absorbed orally
 
- Examples of drugs like penicillin, aminoglycosides.
 
- The gastric acidity destroys these drugs.
 
- Therefore, the intravenous route is preferred
 
Question 2
Correct answer - d) Sartorius
Explanation
- To give an intramuscular injection, the muscle needs to be
large
 
- It should have a good vascular supply.
 
- Most importantly it should be easy to identify the muscle group
superficially.
 
- Sartorius is a thin, slender muscle situated in the thigh.
 
- this makes it difficult to identify superficially ( hence
difficult in slender people, women, and babies)
 
- An important nerve called the femoral nerve is situated very
close to the sartorius muscle.
 
Incorrect:
a) Dorsogluteal -
- it is an important site for intramuscular injection
 
- It the gluteal muscle.
 
- It is highly vascular therefore rapid absorption.
 
- No major nerve in the vicinity
 
b)Vastus lateralis -
- It is the preferred site for intramuscular injection in
patients less than 7 months old
 
- the injection is given in the middle third
 
c) Venogluteal -
- This is the preferred site for injection more than 1 ml and
oily injection
 
- The palm of the hand is placed over the greater trochanter
 
- Right hand for the left hip (patients) and vice versa
 
- Place the index finger over the anterior superior iliac
spine
 
- and move the middle finger over the iliac crest
 
- The injection is giving in the middle of the triangle
 
Question 3
Correct answer - (b) Lower arms
Explanation
- the lower arm doesn't have must fat deposits
 
- It may be vascular leading to rapid drug absorption. This is a
problem because subcutaneous injections are given so that the drugs
are slowly absorbed.
 
- the lower arm as important nerves that supply the hand, they
might get injured
 
Incorrect answer:
a,c,d
All these sites are good sites for subcutaneous injections
Question 4
Correct answer - a
Explanation
- With the help of the fingers of the non-dominant hand, the skin
besides the injection site is depressed.
 
- With other hand, the injection is given at an angle of 90
degrees to the skin.
 
- After the plunger is pushed, the injection is withdrawn from
the muscle
 
- and the finger is released
 
- This disrupts the tract the needle of the injection
created
 
- this blocks the drug from coming out.
 
Incorrect answer:
b) this method has nothing to do with the rapidity of drug
administration.
c) yes a part the method requires the depress the skin, but that
is not the goal of this method
d) This method may not work close to a bone or a joints, as the
muscle mass near these structures may be loss