Question

In: Biology

Imagine that you are studying the metabolism of a baby who is feeding on breast milk....

Imagine that you are studying the metabolism of a baby who is feeding on breast milk. You are going to compare the catabolism of two molecules of galactose from the lactose in milk with the catabolism of two molecules of leucine from the casein of milk.

1. Detail the catabolic path * for the molecules until their final oxidation in CO2 + urea.

2. It includes all the reactions that are carried out and the enzymes that they catalyze.

3. Include the molecular structure and the name of all the intermediaries.

4. All of them must be intertwined. Use different colors for reactions that are (a) only from galactose catabolism (b) only from leucine catabolism and (3) common to both.

5. Finally, detail the net ATP gain from the complete oxidation of each of the molecules. (Include payment for making the urea molecule.) ***i need this part***

Solutions

Expert Solution

2x Galactose to 2x glucose 1 phosphate-------- 2 ATP consumed and 4 NADH formed

2x Fructose 6 p to fructose 1, 6 bis p ------------2 ATP consumed

6C to 3C step doubled the number of molecules

4x Glyceraldehyde 3-phosphate to 1,3-Bisphosphoglycerate------------------------ 4 NADH formed

4x1,3-Bisphosphoglycerate to pyruvate------------------------8 ATPs formed

4x puruvate to Acetyl CoA------------------------ 4 NADH formed

4 Actyl CoA in kreb cycle-------------------------12 NADH fromed+ 4 FADH2 formed + 4 GTP (eq to ATP) is formed

Total NADH formed= 24 eq to 24x2.5=60 ATPs

Total FADH2 formed=4 eq to 4x1.5= 6

Total net ATP = formed –consumed= 12-4=8 ATPs

Total ATP=74

2xLeucine to 2x Acetyl CoA (enter Kreb cycle)+ amino containing part enters urea cycle by releaseing ammina

2x Acetyl CoA produces (3 NADH 1 FADH2 and 1 ATP)x2= (7.5 ATP+1.5 ATP+1 ATP)x2= 20 ATP with two molecules of Leucine.

One ammonia molecule to make urea consumes 3 ATPs

2 leucine give 2 ammonia 6 ATPs consumed

gladiator answered 2 years ago
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