In: Biology
In a sample of 100 Hawaiians, it was found that 35, 20, and 45 individuals had blood groups MM, MN, and NN, respectively.
Calculate a) the allele frequencies and b) the expected Hardy-Weinberg genotypic frequencies, showing your work. c) How many individuals of each genotype are expected to occur in a population of 100 individuals if the population is in Hardy-Weinberg equilibrium? d) Is this population in Hardy-Weinberg equilibrium? Explain why or why not.
According to Hardy Weinberg
equilibrium, genotype frequency can be calculated as
P2 +q2 +2pq =1
The given data i.e. number of individuals with MM, MN, and NN genotypes are not matched with the no. of individuals calculated by the Hardy Weinberg equilibrium,
The allele frequency can be calculated as
p = (No. of MM genotype + No. of MN genotype/2)/Total Number
q = (No. of NN genotype + No. of MN genotype/2)/Total Number
p + q = 1