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The economic burden of influenza disease is recognized as one of the major public health problems...

The economic burden of influenza disease is recognized as one of the major public health problems globally. Much less is known about the economic burden of influenza.
World Health Organization WHO publicized a Manual for estimating the economic burden of seasonal influenza to support the standardization of estimates of the economic burden of seasonal influenza across countries.
The following article “Rationale and opportunities in estimating the economic burden of seasonal influenza across countries using a standardized WHO tool and manual” aims to describe the rationale of the WHO manual development and opportunities that lie in collecting data to help policymakers estimate the economic burden of seasonal influenza. It also links to relevant literature and tools to ensure robustness of applied methods to assess the economic burden associated with seasonal influenza, including direct medical costs, direct non-medical costs and indirect costs.

Read this article and briefly describe the following points:
1. Article summary (introduction- subject- conclusion).
2. The WHO Manual for estimating the economic burden of seasonal influenza.
3. What is the economic burden estimation?
4. The processes for estimating the economic burden of diseases.

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