What acid base disorder develops when you have renal disease and how will your body compensate?...

What acid base disorder develops when you have renal disease and how will your body compensate? Explain

Expert Solution

Answer.

Metabolic acidosis.

Metabolic acidosis occur when kidneys are unable to remove the acidadequately from your blood.
Kidneys play a important role in maintaining the balance of acids in the body.
This is achieved by removing acid from the body through urine.

Metabolic acidosis.

The primary defect in metabolic acidosis is a reduction in bicarbonate concentration , which leads to a fall in blood pH.

The bicarbonate concentration may be decreased due to its utilization in buffering H+ ions , loss in urine or gastrointestinal tract or failure to be regenerated.

The most important cause of metabolic acidosis is due to an excessive production of organic acids which combine with NaHCO3 and deplete the alkali reserve
.Metabolic acidosis is commonly seen in Severe uncontrolled diabetic mellitus which is associated with excessive production of acetoacetic acid and beta hydroxybutyric acid.

● Compensation Metabolic acidosis.

The acute metabolic acidosis is usually compensated by hyperventilation of lungs.
This leads to an increased elimination of CO2 from the body( hence H2CO3 decrease ).

Sydney Mullin answered 2 months ago

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