Question

What acid base disorder develops when you have renal disease and how will your body compensate? Explain

Answer 1

Answer.

Metabolic acidosis.

• Metabolic acidosis occur when kidneys are unable to remove the acidadequately from your blood.
• Kidneys play a important role in maintaining the balance of acids in the body.
• This is achieved by removing acid from the body through urine.

Metabolic acidosis.

• The primary defect in metabolic acidosis is a reduction in bicarbonate concentration , which leads to a fall in blood pH.

• The bicarbonate concentration may be decreased due to its utilization in buffering H+ ions , loss in urine or gastrointestinal tract or failure to be regenerated.

• The most important cause of metabolic acidosis is due to an excessive production of organic acids which combine with NaHCO3 and deplete the alkali reserve
• .Metabolic acidosis is commonly seen in Severe uncontrolled diabetic mellitus which is associated with excessive production of acetoacetic acid and beta hydroxybutyric acid.

● Compensation Metabolic acidosis.

• The acute metabolic acidosis is usually compensated by hyperventilation of lungs.
• This leads to an increased elimination of CO2 from the body( hence H2CO3 decrease ).