Answer-
According to the given
question-
COX6- Electron
transport chain of mitochondria have four enzyme complexes such as
cytochrome c oxidase, NADH dehydrogenase, coenzyme Q cytochrome c
reductase, and succinate dehydrogenase. the chain also have
coenzyme Q and cytochrome c. In yeart these proteins are encoded by
genes present in nucleus. The gene COX6 coded
cytochrome c oxidase enzyme having subunit VI.
- Atp9p ring is present in the
mitochondrial ATP synthase of yeast which helps in proton
translocation for synthesis as well as hydrolysis of ATP
molecule.
- Atp9p is also present in the three
protein complex as well as with Cox6p. more Atp9p is
present in as form of ring in wild type yeast than the mutant
yeast.
- The mutation in atp10
responsible for blocking the interaction between the
Atp9p ring to the and other component of ATP synthase.
Due to this reason the ring that are formed in a cox6
mutant are reduced because Cox6p play an important role in
oligomerization of Atp9p.
- Atp9p interact with F1 ATPase after
oligomerization to form the ring. After interaction thay
form F1-Atp9p ring which combine with the other component such as
Atp6p, Atp8p, except OSCP. Cox6p and Atp9p are responsible for
formation of ATP synthase and COX respectively.
- Atp9p oligomerization to form
ring in ox6 mutant mitochondria are less
effective that the wild type when compared to study the effect
under glucose-repressed conditions.
- cox6 mutant have less
Atp9p which are associated with ring in cox6 that are new
translated and their assembly of ring are also less efficient than
the wild type because Cox6p helps in assembling of ATP synthase
enzyme and this is responsible for increaing the efficiency of ring
formation.