Question

In: Nursing

The following lab results were found in a patient with mild weight loss and nausea and...

The following lab results were found in a patient with mild weight loss and nausea and vomiting, who later developed jaundice and an enlarged liver.

total serum bilirubin

elevated

AST

markedly elevated

ALT

moderately elevated

anti-HAV IgG

positive

anti-HAV IgM

negative

HBsAg

positive

anti-HBs

negative

HBcAb Ig

positive

HBcAb IgG                                               

negative

Questions:

  1. What is the most likely diagnosis?
  2. What is the prognosis?
  3. What additional markers would be helpful to know for the prognosis?

Solutions

Expert Solution

1. Most likely diagnosis

Hepatitis B :

It is an acute form of Hepatitis , transmitted by blood , body fluids and sexual contact and is a potentially fatal liver infection caused by Hepatitis B Virus . The symptoms may vary from one person to another, and the common symptoms are yellowish discoloration of the eyes and dark urine, abdominal pain , nausea , vomiting etc.

2. Prognosis:

There is no cure for the Hepatitis B Virus , once it is contracted. But the patient can recover fully from the symptoms through proper treatment . Children and infants are in risk to  develop chronic hepatitis infection.

3. Additional markers :

Laboratory tests revealed that HBs Ag ( Hepatitis surface Antigen) is positive , that indicates the present infection with Hepatis B Virus.

Additional markers:

* HBe Ag - Hepatitis B e Antigen, presence indicates viral replication and therefore the risk of transmission.  

* HBcAg -Hepatitis B core antigen presence indicates the positive result for Hepatitis B infection.

* HBV DNA level : indicates the liver disease activity.


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