Question

The use of opioid medications and drugs have had a long and storied past in the United States. These drugs are all linked together by the common threat of the opioid poppy. For this assignment, you will put together a creation timeline of the each of the associated opioid drugs commonly used in the United States. In step one of this assignment, you must chronologically order following drugs in a true timeline with the specific year or decade included:

1. Codeine
2. Heroin
3. Methadone
4. Morphine
5. Oxycodone
6. Vicodin

As you order the drugs, please include the following information with each drug:

• Where is each drugs scheduled?
• List the different ways in which the drug can be administered. If there is more than one way to use the drug, list them all.
• What are three of the short term pharmacological symptoms of using each of these drugs?
• What are three symptoms of withdrawal?

Like previous assignments, this timeline should be created using formal language and no slang. As much of this information is not common knowledge you should be citing and providing references in proper APA format. All of the content for this assignment should be contained to one page, with the references being the only information listed on a second page (if need be).

I am still looking for creativity in this assignment like the others – this means color, pictures, and anything else you want to use that makes your assignment stand out. A good idea would be to include pictures of each of the individual drugs. You can create your slide in either portrait or landscape form and then submit it as a PDF document.

Grading Rubric (10 total points)

Criteria	Points
Are the drugs in the proper chronological order with the correct years?	2 points
Does the student answer the scheduling of each of the drugs?	2 points
Does the student discuss the different ways in which each of the drugs can be administered?	2 points
Does the student identify three short term pharmacological symptoms of the drug, and three symptoms of withdrawal?	2 points
Originality and formatting of the assignment	2 points
	10 points total

Answer 1

Morphine was developed in the year 1803-1805 by friedrich serturner

Codeine was developed in the year 1833 by pierre jean robiquet

HEROIN was invented from morphine in the year 1874 C R lader wright

Oxycodone was made in the year 1916

Vicodin was discovered in the year of 1920

Methadone was discovered in the year 1937 IG FarbenindustrieAG

Morphine: it is discovered in the year in 1803-1805. It is scheduled under II. It has been administered in the forms of Per Oral(adults) 10-30 mg every 4 hourly, and for Intramuscular , Subcutaneous in case of adults 5-20mg every 4hourly,and for Subcutaneous in the case of children 100-200mcg/kg every 4hourly Intravenously (adults) 2.5mg-15mg q 4hr or Intravenous infusion initially with a loading dose of 15mg followed by infusion at 0.8mg-10mg/hr, and for Intramuscular/Intravenous in case of children 50-100mcg/kg and Rectal forms in case of adults 10-30mg/4hourlyr Epidural in case of adults 2-10mg/day for initial dose and continuous dose 2-4 mg/day Intrathecal 0.2mg-1mg.and It has been administered for the three short symptoms such as anxiolytic, severe pain, restlessness and aggressive behavior. Three withdrawal symptoms are lacriamtion, anxiety, muscle and bone pain, tachycardia, high blood pressure

Codeine

It is made in the year of 1833. It is scheduled under II, III, IV, and V. It is administered via Per Oral, Intramuscular, Subcutaneous and it is available in the form of Tablets: 15mg, 30mg, 60mg and Oral solution; 10mg/5ml, 15mg/5ml and Injection 30mg/ml, 60mg/ml. it has been administered for relieving of short symptoms such as cough reflex, sedative, severe pain. It has been identified that it has following withdrawal symptoms such as lacrimation, sweating, anxiety, tachycardia, high blood pressure

Heroine: it is discovered in the year 1874. It is scheduled under class I. it is banned and it is illegal to use anywhere. It has been administered by patient himself for relieving of sedation, restlessness, and bone and muscle pain. Increased lacrimation, sweating, restlessness, tachycardia, high blood pressure are the withdrawal symptoms of the heroin after withdrawal of medication

Oxycodone: it is discovered in the year 1816. It is scheduled under class II. It is available and administered in the form Tablets 5mg, concentrated oral solution are 20mg/ml and Suppositories. it is available in the combination of Oxycodone/paracetamol Tablets are 5mg oxycodone with 325mg acetaminophen and in the Capsules form 5mg oxycodone with 500mg acetaminophen and in the Oral solution are 5mg oxycodone with 325 mg acetaminophen/5ml and in the Oxycodone/aspirin combination are tablets 2.44mg oxycodone with325mg of aspirin and 4.88 mg oxycodone with 325mg aspirin. It has been prescribed in order to relieve symptoms of moderate and severe pain, sedative, restlessness in the case of aggressive behavior. It is identified that it has showed following withdrawal symptoms such as increased lacrimation, tachycardia, hypertension, muscle and bone pain, sweating.

Vicodin. It is made in the year 1920. It is scheduled under III. It is administered per oral and it is available in the form of Tablets and its doses are 2.5mg, 5mg, 7.5mg, 10mg and it is available in combination with aspirin and acetaminophen such as Liquids, syrup, suspensions forms. It has been administered for the sedative, moderate and severe pain, hypnotics. It has been identified that it has showed following withdrawal symptoms such as increased lacrimation, tachycardia, hypertension, nervousness, anxiety.

Methodone: it is made in the year 1937. It is scheduled under II. It has been administered in the form Per Oral , Intra muscular, Subcutaneous form and it is has been used for Detoxification purpose and is given in the form Per Oral 15-40mg mg/day initially for 2-3 days, then decreased every 2 days and Maintenance dose Per Oral 20-120mg /day and it is available in the form of Tablets such as 5mg 10mg and in the form of Dispensable tablets 40mg and in the form Oral soluion5mg/5ml, 10mg/5ml and Oral concentrate 10mg/ml. it has been administered for relieving symptoms such as moderate to severe pain, sedative purpose and aggressive behaviour. It has been identified that it has shown following withdrawal symptoms such as increased   lacrimation, sweating, anxiety, tachycardia, high blood pressure, restlessness, muscle and bone pain

Medicine name	morphine	codeine	heroin	oxycodone	vicodin	methddone
Scheduled	II	II, III, IV, V	I	II	III	II
Different forms of administration	PO (adults) 10-30 mg every 4 hourly IM, SC(adults) 5-20mg every 4hourly SC(children) 100-200mcg/kg every 4hourly IV (adults) 2.5mg-15mg every 4hourly or IV infusion initially with a loading dose of 15mg followed by infusion at 0.8mg-10mg/hr IM/IV (children 50-100mcg/kg Rectal (adults) 10-30mg/4hr Epidural (adults) 2-10mg/day for initial dose and continuous dose 2-4 mg/day Intrathecal 0.2mg-1mg	Tablets : 15mg,30mg, 60mg Oral solution 10mg/5ml,15mg/5ml Injection 30mg/ml, 60mg/ml Iti is administered via PO, IM, SC	Injection and Powder forms	Tablets 5mg Concentrated oral solution :20mg/ml Suppositories Oxycodone/paracetamol Tablets: 5mg oxycodone with 325mg acetamiophen Capsules 5mg oxycodone with 500mg acetaminophen Oral solution: 5mg oxycodone with 325 mg acetaminophen/5ml Oxycodoen/aspirin: tablets 2.44mg oxycodoen with325mg of aspirin, 4,88 mg oxycodone with 325mg aspirin	It is administered per oral Tablets: 2.5mg, 5mg, 7.5mg, 10mg In combination with aspirin and acetaminophen Liquids, syrup, suspensions	PO, IM,SC Detoxification PO 15-40mg mg/day initially fo2-3 days, then decreased every 2 days Maintainence PO 20-120mg /day Availability Tablets 5mg 10mg Dispensible tablets 40mg Oral soluion5mg/5ml, 10mg/5ml Oral concentrate 10mg/ml
Three symptoms of short administration	Sedation, analgesic, hypnotics	Sedative, reduce cough reflex, analgesic	Sedation, analgesic, hypnotics	Sedation, analgesic, hypnotics	Sedation, analgesic, hypnotics	Sedation, analgesic, hypnotics
Three symptoms of withdrawal	Early symptoms : lacrimation, apnea, sweating, anxiety Later symptoms: High blood pressure, nausea, vomiting diarrhea	Early symptoms : lacrimation, apnea, sweating, anxiety Later symptoms: High blood pressure, nausea, vomiting diarrohea	Restles lessnes, muscle ean d bone pain, cold flashes with good pumps	Early symptoms : lacrimation, apnea, sweating, anxiety L;ater symptoms: High blood pressure, nausea, vomiting diarrohea	Early symptoms : lacrimation, apnea, sweating, anxiety Later symptoms: High blood pressure, nausea, vomiting diarrohea	Early symptoms : lacrimation, apnea, sweating, anxiety Later symptoms: High blood pressure, nausea, vomiting diarrohea