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Which of the following species is attacked by benzene in the electrophilic nitration reaction? (a)HNO3 (b)NO2-...

  1. Which of the following species is attacked by benzene in the electrophilic nitration reaction? (a)HNO3 (b)NO2- (c)NO2+ (d) NO+
  2. Which of the following is the strongest activating group in electrophilic aromatic substitution reactions? (a) CH2CH3 (b) OCH3 (c)CO2CH3 (d) NO2
  3. In electrophilic aromatic substitution reactions a bromine substituent is (a) a deactivator and a m-director (b) a deactivator and an o,p-director (c) an activator and a m-director (d) an activator and an o,p-director

4. List at least two of the limitations associated with the Friedel-Crafts alkylation reaction

5. Which of the following compounds would most likely be used in the preparation of tertiarybutylbenzene? (a) (CH3)2CHCOCl (b) (CH3)3CCOCl (c)CH3CH3CH3COCl (d) CH3CH3COCl

6. Which of the following compounds is least reactive in the nucleophilic aromatic substitution reactions with NaOH? (a)2,4-dinitrochlorobenzene (b)m-nitrochlorobenzene (c)o-nitrochlorobenzene (d)3,5-dinitrochlorobenzene

7. Which mechanism of nucleophilic aromatic substitution reaction proceeds via a benzyne intermediate? (a) addition-elimination mechanism (b)elimination-addition mechanism

8. Which mechanism of nucleophilic aromatic substitution reaction proceeds via a negatively charged Meisenheimer complex? (a) addition-elimination mechanism (b)elimination-addition mechanism

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