Question

Design a cell transduction cascade that communicates the presence of a target organism attacking a crop. The pathway must use a G-protein-coupled receptor (GPCR), Recptor Tyrosine Kinases (RTK), or ion channel protein as a receptor. Make sure you fully illustrate the mechanism.

The cascade must also include: at least six steps (not including initiation); a single binding event that results in a 10,000 fold amplification of the signal (indicate where the amplification occurs); at least two points of negative regulation (you don't need to illustrate the regulation mechanisms); and result in a protein that functions as a transcription factor (TF).

Answer 1