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In: Biology

For each of the gene delivery methods listed below, write Yes or No in the spaces...

For each of the gene delivery methods listed below, write Yes or No in the spaces provided according to whether they have or do not have the features listed.

Question 1 of 31

What follows is a fill in the blank question with 12 blanks.

Can the delivery method be immunogenic?
Retrovirus:  Blank 1. Fill in the blank, read surrounding text.
Adenovirus:  Blank 2. Fill in the blank, read surrounding text.
Liposome:  Blank 3. Fill in the blank, read surrounding text.

Is the delivery method efficient (in terms of seeking out cells as targets)?
Retrovirus:  Blank 4. Fill in the blank, read surrounding text.
Adenovirus:  Blank 5. Fill in the blank, read surrounding text.
Liposome:  Blank 6. Fill in the blank, read surrounding text.

Does the delivery method result in the new gene integrating into the genome?
Retrovirus:  Blank 7. Fill in the blank, read surrounding text.
Adenovirus:  Blank 8. Fill in the blank, read surrounding text.
Liposome:  Blank 9. Fill in the blank, read surrounding text.

Does the delivery method only affect dividing cells?
Retrovirus:  Blank 10. Fill in the blank, read surrounding text.
Adenovirus:  Blank 11. Fill in the blank, read surrounding text.
Liposome:  Blank 12. Fill in the blank, read surrounding text.  

Solutions

Expert Solution

1.Can the delivery method be immunogenic?

Ans:- Yes, Liposome, these are the specialized closed bilayer structures formed by hydrated phospholipids. It is mainly used as artificially delivery systems for drugs or antigens, due to their capability to encapsulate bioactive hydrophilic, amphipathic, and lipophilic molecules into inner water phase or within lipid leaflets. So yes it is immunogenic.

2.Does the delivery method result in the new gene integrating into the genome?

Ans:- yes, Retroviruses. Most are RNA viruses, they carry a gene for a reverse transcriptase enzyme that transcribes the viral genetic material into a double stranded DNA. This DNA intermediate is then incorporated into the host DNA.

3.Is the delivery method efficient (in terms of seeking out cells as targets)?

Ans:- yes, liposomes, mediated transfer is more efficient. Because is carry particular drug for perticular site.

4.Does the delivery method only affect dividing cells?

Ans:- no. It can effect all kinds of cells.

I hope this answer will definitely help you. Please give me likes. All the best. THANK YOU STAY SAFE.

gladiator answered 2 years ago
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