Question

Vesicles in eukaryotic cells can move along microtubules, using the ATPases kinesin and dynein. The figure at right depicts a microtubule aster nucleated from a centrosome, with a transport vesicle moving along the microtubule. The + and – ends of that microtubule are indicated.

A. Which microtubule motor protein would be used to transport the vesicle away from the centrosome?

B. Which motor protein do you think would power:

1. Vesicle transport from the ER to the Golgi?

2. Vesicle transport from the Golgi to the plasma membrane?

Phosphorylation of nuclear lamins regulates their assembly and disassembly during mitosis. You add a drug to cells that are undergoing mitosis that inhibits the activity of an enzyme that dephosphorylates nuclear lamins. Briefly, predict will happen to these cells. Why?

Answer 1