Question

In: Anatomy and Physiology

Which statements would also be true about the effects of fasciculin? Check all that apply. Group...

Which statements would also be true about the effects of fasciculin? Check all that apply.

Group of answer choices

It would cause more calcium to be released fron the sarcoplasmic reticulum

It would increase the amount of ACh in the synapse

It would decrease the amount of ACH in the synapse

It would increase parasympathetic output

It would increase sympathetic output

It would decrease parasympathetic output

It would decrease sympathetic output

It would have influence on autonomic output

Solutions

Expert Solution

B) It would increase the amount of ACh in the synapse

D) It would increase parasympathetic output

E) It would increase sympathetic output

h) It would have influence on autonomic output

Explanation: Fasciculins are a class of toxic proteins found in certain snake venoms. It attaches to molecules of the acetylcholinesterase in the muscles and their neuromuscular junctions, and thereby interferes with their necessary neuromodulatory inhibition. It disrupters of acetylcholine neurotransmission generally penetrate the neuromuscular junction, where they interfere with either the production or reception of acetylcholine, or the hydrolysis of acetylcholine after it has achieved its function of neurotransmission; mamba fasciculins prevent the final stage of this process by binding to acetylcholinesterase and blocking its action on acetylcholine leading increase level of acetylcholine in the synapse; the result is that after the acetylcholine has transmitted the required stimulus.

- it can increase the sympathetic output by increasing the presynaptic stimulation by the acetylcholine


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