Question

In: Mechanical Engineering

What is the answer to this question? Imagine if an artificial cartilage is fully made of...

What is the answer to this question?

Imagine if an artificial cartilage is fully made of chondrocytes which has a compression modulus 0.41 KPa and apparent viscosity of 3.0 KPa.s.

a) If such a artificial cartilage is under a sudden load stress of 0.1 KPa, use a simple Kelvin model, can you give an estimate of the time period needed to equilibrium from the given mechanical properties?
b) What is the final equilibrium strain?

c) Plot out the creep function (strain/load stress) of this cartilage under a sudden load stress of 0.1 MPa at time t=0.
You can modify the sample Matlab skeleton code below.
syms sig0 eps emod mvis

dsolve('Deps + (emod/mvis)*eps = sig0/mvis') emod=0.1;
mvis=1.0;
sig0=1.0;

C5=1.0;
t=0:1:100;
epsresult=(sig0 - C5*exp(-(emod*t)/mvis))/emod plot(epsresult,t);

d) Comment on why a good artificial cartilage can not be made with only chondrocytes and what is missing.

Solutions

Expert Solution

a) For a step load, the strain relation for Kelvin model is

Where

= initial stress=0.1 kPa

= relaxation time constant

Here

= apparent viscosity=3 kPa.s

k=compression modulus=0.41 kPa

From the above relation, it is seen that the strain will reach about 99% of steady state value after a time of =36.59 s

The Kelvin model is shown below:

b) The equilibrium strain is given as

c) The creep function is given as

The above is plotted below:

The workspace screenshot is given below:

d) For any applied stress, it will take a very long time for the strain to reach the steady state value and in the meanwhile the cartilage is under deformation. This may affect the stability of the particular body part under load. Hence a good cartilage can not be made with chondrocytes. Also the relaxation of stress property (for an applied constant strain) is missing from this model.


Related Solutions

What are the three disadvantages of having a Skelton made of cartilage only? for example, in...
What are the three disadvantages of having a Skelton made of cartilage only? for example, in cartilaginous fishes.
please answer the question : Explain fully, with examples, what dollar cost averaging is. What will...
please answer the question : Explain fully, with examples, what dollar cost averaging is. What will happen (1) if the price of an investment trends down overtime; (2) trends up; (3) trends down then up; and (4) in real life? Use excel to model and graph the result.
10) Answer the following briefly: a) What are the three types of cartilage and what distinguishes...
10) Answer the following briefly: a) What are the three types of cartilage and what distinguishes them from one another? Can you identify a histological section of them? b) Aside from structural support what are other functions of bone? c) What are two ways to view bone histologically? 4. What are the 2 methods of ossification, their process and how they differ. d) What does an osteoclast actually do and what are the morphological zones we talked about? e) How...
What is the structure of the cartilage?
What is the structure of the cartilage?
please answer the question correct: Explain fully, with examples, what dollar cost averaging is. What will...
please answer the question correct: Explain fully, with examples, what dollar cost averaging is. What will happen (1) if the price of an investment trends down overtime; (2) trends up; (3) trends down then up; and (4) in real life? Use excel to model and graph the result.
What is the difference between producer surplus and economic profits? Please answer the question fully and...
What is the difference between producer surplus and economic profits? Please answer the question fully and in detail for a rating. Thank you.
Imagine that you are designing a scaffold for cartilage tissue engineering? Describe the requirements of engineered...
Imagine that you are designing a scaffold for cartilage tissue engineering? Describe the requirements of engineered scaffolds for cartilage tissue engineering application. How would you manufacture that desired scaffold? Briefly explain manufacturing method. You will have to use a proper bioreactor system to increase adaptivity of cartilage scaffold to in vivo conditions. Please define what type of bioreactor you need to use. What are the demands that tissue engineering bioreactors have to meet? Would you prefer static or dynamic cell...
can you answer this question correct: Explain fully, with examples, what dollar cost averaging is. What...
can you answer this question correct: Explain fully, with examples, what dollar cost averaging is. What will happen (1) if the price of an investment trends down overtime; (2) trends up; (3) trends down then up; and (4) in real life? Use excel to model and graph the resu
(answer with a paragraph or a few sentences for each) 1. The structure of cartilage (in...
(answer with a paragraph or a few sentences for each) 1. The structure of cartilage (in general), how types of cartilage differ from one another, and the importance of the perichondrium associated with cartilage 2. The activity of osteoblasts, balancing osteoclast activity with osteoblast activity, and ways through which various signal molecules control osteoclast activity 3. Comparison of cartilage and bone (particularly a long bone) with respect to the blood supply that supports cells of the tissue
Answer this question fully and PLEASE FOLLOW MY CHART in the same order, type your answer....
Answer this question fully and PLEASE FOLLOW MY CHART in the same order, type your answer. thanks Effect of transactions on current position analysis Data pertaining to the current position of Forte Company follow: Cash $412,500 Marketable securities 187,500 Accounts and notes receivable (net) 300,000 Inventories 700,000 Prepaid expenses 50,000 Accounts payable 200,000 Notes payable (short-term) 250,000 Accrued expenses 300,000 1. Compute (a) the working capital, (b) the current ratio, and (c) the quick ratio. Round to one decimal place....
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT