If an autoimmune condition affects Type 3 immunity, therapies such as anti-IL-17 or anti-IL-23 may be...

If an autoimmune condition affects Type 3 immunity, therapies such as anti-IL-17 or anti-IL-23 may be effective. True or False?

Solutions

Expert Solution

True

Psoriasis is an inflammatory skin disease, and psoriatic arthritis (PsA) is an inflammatory arthritis, which share clinical , genetic and pathogenic factors and it is summed as one disease as psoriatic diseases.
Interleukin (IL)-17 plays a major role in the development of both psoriasis and PsA.
Interleukin (IL)-23 is important in the proliferation and maintenance of IL-17 , and therefore, cytokines of the IL-23/ IL-17 axis attracted much interest as therapeutic targets in psoriais and PsA.
Therapeutic agents targeting the IL-23/IL-17 axis have been proven to be very effective in psoriais and PsA.
Some agents target IL-23 and other IL-17 including , anti-IL-12/IL-23 p40 (ustekinumab, briankizumab), anti-IL-23p19 (guselkumab, tildrakizumab, risankizumab, brazikumab, mirikizumab), anti-IL-17A (secukinumab, ixekizumab), dual anti-IL-17A and anti-IL-17F (bimekizumab), or anti-IL-17 receptor (brodalumab) monoclonal antibodies

Sydney Mullin answered 9 months ago

Next > < Previous

Related Solutions

23-17 (Objectives 23-3 , 23-4) The following are misstatements that might be found in the client’s...

23-17 (Objectives 23-3 , 23-4) The following are misstatements that might be found in the client’s year-end cash balance (assume that the balance sheet date is June 30): 1.A check that was dated June 26 and disbursed in June was not recorded in the cash disbursements journal, but it was included as an outstanding check on June 30. 2.A check was omitted from the outstanding check list on the bank reconciliation. It cleared the bank September 6. 3.The outstanding checks...

1). Type II diabetes may result from a). obesity, b). autoimmune attack on alpha cells, c)....

1). Type II diabetes may result from a). obesity, b). autoimmune attack on alpha cells, c). autoimmune attack on beta cells, d). autoimmune attack on alveolar epithelial cells, e). none of the above 2). In what week of human development does gastrulation occur? a). first, b). fourth, c). third, d). second, e). fifth 23). The wet form of macular degeneration may be slowed by a). lycopene, b). vitamin K, c). lutein, d). anti-VEGF drugs, e). c and d

Discuss both Picasso's Guernica and Goya's Executions of May 3, 1808 as anti-war artworks. What are...

Discuss both Picasso's Guernica and Goya's Executions of May 3, 1808 as anti-war artworks. What are the historical circumstances for each? In what ways are they different? How are they the same?

3. Identify the type of bias that may occur in the following situations. a) A survey...

3. Identify the type of bias that may occur in the following situations. a) A survey question asks, “How many words per minute can you read?” b) A survey is sent to parents of school-age children that asks whether bus safety lanes should be installed. c) A phone company surveys its customers via text message about which services people like the best. d) A survey asks, “Now that the city is in debt, do you think the current mayor will...

Subjects