Question

In: Biology

"nephrotic syndrome is a genetic disorder that requires two alleles to inherit. In germany 1 in...

"nephrotic syndrome is a genetic disorder that requires two alleles to inherit. In germany 1 in 7000 people to have it. How many people are expected to have the heterozygous genotype in germany described?"

How would I first analyze this question to get to the answer? please leave a detailed explanation. Greatly appreciated

Solutions

Expert Solution

in these types of question, you should first extract the calculative part of data. then you applying hardy weinberg equation.

see what we can deduce from the question.

nephrotic syndrome is an autosomal recessive disorder which occur in 1 out of 7000 people.

so if we suppose p as a dominant allele and q as a recessive

then applying the appropriate hardy Weinberg equation

always start with homozygous data that will be easy

i trid to explain it at your level. if still you have any confusion then you can ask.


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