Neurons to act as integrators. Discuss the concepts of
facilitation temporal and spatial summation and convergence...
Neurons to act as integrators. Discuss the concepts of
facilitation temporal and spatial summation and convergence in the
context of integration
Solutions
Expert Solution
Spatial and temporal summation are the two types of summation
and it is a process which determine whether or not an action
potential will be genrated by an action potential will be generated
by the combined effects of excitatory and inhibitory signals . both
from multiple simultaneous input (spatial summation ) and from
repeated inputs (temporal summation ).
Depending on the sum total of many individual input , summation
may or may not reach the threshold voltage to trigger action
potential
There are two types of neurotransmitter released from the
presynaptic neuron , they are excitatory neurotransmitters which
produce depolarization of the postsynaptic cell, whereas the
hyperpolarization produced by an inhibitory neurotransmitter will
mitigate the effects of an excitatory neurotransmitter.
This depolarization is called an EPSP, or an excitatory
postsynaptic potential, and the hyperpolarization is called an
IPSP, or an inhibitory postsynaptic potential.
Spatial summation is the mechanism of eliciting of action
potential in a neuron with an input from multiple presynaptic
cells.It is the algebraic sum of potentials from
different areas of input, usually on the dendrites.
Temporal summation occur when high frequency action potentials
in the presynaptic neuron elicits postsynaptic potentials
which summate with each other.
Gluatamate is an example of excitatory neurotransmitter and
GABA is an example of inhibitory neurotransmitter.
Describe EPSP’s and IPSP’s and how spatial and temporal
summation relate to EPSP’s and IPSP’s. Include a discussion of how
EPSP’s lead to an action potential.