Question

In: Chemistry

PCP has many analogs. Research two PCP analogs and write up a synthesis route for each....

PCP has many analogs. Research two PCP analogs and write up a synthesis route for each. Include information about precursor availability, by products, yield, difficulty of reaction, and hazards.

Solutions

Expert Solution

PCPs are drugs called as arylcyclohexylamines.

used as a surgical anaesthetic in both humans and veterinary practice,

They are not currently manufactured and has been placed under Schedule II of the Controlled Substance Act in the US.

PCP analogues:

ketamine, tiletamine, PCPy, TCP, and PCE, as well as TCPy

synthesis route ketamine

precursor availability == cyclohexanone, methylamine and chloro- benzonitrile easy available in alternative forms and produce a long effect

by-products= impurities amphetamine, methamphetamine

yield = 60%

the difficulty of reaction = production is difficult so production through the illicit market is reduced

and hazards = out of 10 it is rated 2


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