In: Biology
6) Fill in the blanks AND put the following steps of DNA replication in the correct order
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DNA Replication Steps |
RNA primers are removed and gaps are filled by DNA polymerase. |
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______________________ starts adding nucleotides to the 3' end of the primer. |
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The gap between the two DNA fragments is sealed by __________________, which helps in the formation of phosphodiester bonds. |
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Elongation of both the lagging and the leading strand continues. The continuously synthesized strand is known as the _______________strand. The ___________ strand is replicated away from the replication fork, in small fragments known as ______________ fragments, each requiring a primer to start the synthesis. |
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_________________ binds at the region ahead of the replication fork to prevent supercoiling. |
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An enzyme called _____________ unwinds the DNA by breaking the ____________ bonds between the nitrogenous base pairs. Two Y-shaped replication forks are formed at the origin of replication and these get extended bi-directionally as replication proceeds. |
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______________________ binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. |
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Primase synthesizes ___________________complementary to the DNA strand. |
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There are specific nucleotide sequences called ____________ of replication where replication begins. |
RNA primers are removed and gaps are filled by DNA polymerase. |
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_DNA polymerase_starts adding nucleotides to the 3' end of the primer. |
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The gap between the two DNA fragments is sealed by _DNA Ligase_, which helps in the formation of phosphodiester bonds. |
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Elongation of both the lagging and the leading strand continues. The continuously synthesized strand is known as the _Leading _strand. The _Lagging_ strand is replicated away from the replication fork, in small fragments known as __Okazaki__ fragments, each requiring a primer to start the synthesis. |
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__Topoisomerases__ binds at the region ahead of the replication fork to prevent supercoiling. |
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An enzyme called _Helicase_ unwinds the DNA by breaking the __Hydrogen__ bonds between the nitrogenous base pairs. Two Y-shaped replication forks are formed at the origin of replication and these get extended bi-directionally as replication proceeds. |
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_SSBs__ binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. |
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Primase synthesizes _RNA primer_complementary to the DNA strand. |
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There are specific nucleotide sequences called _Origin_ of replication where replication begins. |