In: Biology
What are retroviruses? How do they reproduce and what is the role of the enzyme reverse transcriptase?
Retroviruses are single stranded positive sense RNA virus , which are obligate parasite target a host cell.
Structure:-
The viruses consists of an outer envelope. The envelope is composed of lipids. Also there present glycoprotein.
Genome- the genome is diploid , composed of two identical single stranded v, positive sense RNA copies. In association with the viral RNA there present a enzyme called reverse transcriptase.
The genome is sorrounded by a nucleocapsid.
Reproduction-
It has enter a host cell before it gets multiplied.
In the host cell, the viral RNA is transcribed by the enzyme reverse transcriptase , first into single-stranded DNA and then to double-stranded DNA which integrates into the host cell chromosome. Here VIRAL RNA get transcribed into DNA.
The double stranded DNA is now called a pro viruses.
The provirus then with the help of host protein synthesis mechinary , makes viral nucleic acid and proteins.
Then viron assembly occurs in the host cell. At this stage only nucleocapsid is complete . Envelope are derived from host cell membrane during the process of budding.
So in this way New viruses are produced and viruses leave one host cell and infect other cell.