Question

In: Biology

Describe the molecular mechanism by which high energy charge in the cell inhibits the activity of...

Describe the molecular mechanism by which high energy charge in the cell inhibits the activity of the pyruvate dehydrogenase (PDH) complex. Explain why metabolic regulation of PDH makes sense with regard to controlling metabolic flux through the citrate cycle.

Solutions

Expert Solution

gladiator answered 1 year ago
Next > < Previous

Related Solutions

Define, describe, and explain the importance of low versus high energy charge. Why can’t a cell...
Define, describe, and explain the importance of low versus high energy charge. Why can’t a cell just make as much ATP as it wants and keep the ATP on hand until it is needed?
which of the following cell transport mechanism requires a transport protein, but not energy?     A-...
which of the following cell transport mechanism requires a transport protein, but not energy?     A- facilitated diffusion.     B- osmosis     C- active transport.     D- diffusion.     E- secondary active transport.
1 a. What is meant by “energy charge” of a cell? b. Describe two conditions that...
1 a. What is meant by “energy charge” of a cell? b. Describe two conditions that would indicate a low cell energy charge? c. What effect does a low energy charge have on cellular metabolism? Explain. d. How many ATP are produced from the complete oxidation of pyruvate? 2. Glucose and fructose are both carbohydrates. Discuss the similarities and differences between them. What is their isomeric relationship? What type of ring structures does each tend to form? What is sucrose?...
Describe the molecular mechanism of skeletal muscle contraction in detail.
Describe the molecular mechanism of skeletal muscle contraction in detail.
Describe how a bacterial cell could harvest and convert the unstable high energy electrons contained in...
Describe how a bacterial cell could harvest and convert the unstable high energy electrons contained in the redox cofactors to ATPs.
Regulation of GNG and glycolysis Describe how high energy charge favors gluconeogenesis over glycolysis based on...
Regulation of GNG and glycolysis Describe how high energy charge favors gluconeogenesis over glycolysis based on the ratio of [ATP]/[AMP] of high energy charge and allosteric regulation (McKee page 298). Describe how low energy charge measured by low ratio of [ATP]/[AMP] inhibits the rate of GNG based on allosteric regulation of fructose 1,6 bisphosphatase by AMP. Compare the rates of GNG and glycolysis in a liver cell with low energy charge based on allosteric regulation. Differentiate between the blood concentrations...
Describe the mechanism of action of the drug ZAVESCA Briefly describe the normal cell biology, the...
Describe the mechanism of action of the drug ZAVESCA Briefly describe the normal cell biology, the pathogenic state and how the drug alters the pathogenic state. Come up with an experimental plan by which you can prove where in the cell the drug acts; what cellular functions it modulates, and the mechanism by which it works.
Describe the molecular mechanism for the expression of the two alternate cellular proteins in different tissues...
Describe the molecular mechanism for the expression of the two alternate cellular proteins in different tissues of a heterozygote human female. Why do such alternate cellular phenotypes not appear in the female homozygote?
Describe the molecular mechanism for the expression of the two alternate cellular proteins in different tissues...
Describe the molecular mechanism for the expression of the two alternate cellular proteins in different tissues of a heterozygote human female. Why do such alternate cellular phenotypes not appear in the female homozygote? This is the question that was asked by my professor.
Suppose that a molecular ion with charge -10e is embedded within the 5.0-nm-thick cell membrane of...
Suppose that a molecular ion with charge -10e is embedded within the 5.0-nm-thick cell membrane of a cell with membrane potential -70 mV. What is the electric force on the molecule?
ADVERTISEMENT
Subjects
ADVERTISEMENT
Latest Questions
ADVERTISEMENT