A combination of nephrotoxic drugs and metformin contributed to Sharon’s rapid decline. Glomerulonephritis is characterized by...

A combination of nephrotoxic drugs and metformin contributed to Sharon’s rapid decline. Glomerulonephritis is characterized by inflammation of the glomerulus, leading to increased vascular permeability. Describe how glomerulonephritis will impact the process of filtration in the nephron. What is the impact on GFR? Predict blood and urine albumin levels, and discuss how glomerulonephritis will impact fluid and nutrient exchange in systemic capillaries. How does this cause edema in many patients with glomerulonephritis?

Expert Solution

Answer :)

Glomerulonephritis causes a reduction in the filtering process and hence decreased glomerular filtration rate (GFR). It is because a fall in GFR is accredited to drops in the filtering surface area, and possibly the Kf i.e. glomerular capillary ultrafiltration coefficient, which can result from irreversible structural damage, reversible mesangial cell (MC) contraction, or a combination of both.

Due to glomerulonephritis, waste and electrolytes build up in the blood. Therefore, blood volume is increased in this condition. Due to fluid retention, the urine volume is decreased.

Acute glomerulonephritis causes heart failure due to significant hypertension. Blood volume is increased in glomerulonephritis patients and that causes pressure on the systemic capillaries to filter more blood.

Due to increased blood volume, fluid retention occurs in the area around blood vessels. This causes edema.

Sydney Mullin answered 1 year ago

Two antidibetic drugs (Amylin and Metformin) are compared to check more effectiveness. Amylin was intake by...

Two antidibetic drugs (Amylin and Metformin) are compared to check more effectiveness. Amylin was intake by 12 patients [Note: The average glucose level=120 mg/dL and standard deviation=15 mg/dL] and Metformin was intake by 30 patients [Note: The average glucose level=105 mg/dL and standard deviation=20 mg/dL]. Can we say that Amylin is more effective than Metformin at 95% CL.?

Factors that have contributed to the decline of non-money-based culture

How has money has become the focal point of modern world culture and ssociety, especially in the Western world

What is NAFTA and how does NAFTA contributed to the decline of manufacturing industries in Canada?

(History of Economic Thought) Questions 1-) What wre the factors that contributed to the decline of...

(History of Economic Thought) Questions 1-) What wre the factors that contributed to the decline of the feudal system? 2-) What were the two phases of mercantilism? Give dates for these phases. What was the focus of the economists in these phases? 3-) What are the three classes that we see in the Tableau? Define and explain each briefly. 4-) According to Adam Smith, does the amount of direct and inirect labor used up in the production of a commodity...

Which resource is likely to have contributed to South Korea's rapid economic growth?

Is the dose-response relationship for most psychoactive drugs characterized by a threshold model or a linear...

Is the dose-response relationship for most psychoactive drugs characterized by a threshold model or a linear model? Explain your answer.

Rapid ascent during diving can trigger decompression sickness. This condition is characterized by production of nitrogen...

Rapid ascent during diving can trigger decompression sickness. This condition is characterized by production of nitrogen bubbles in blood that can seriously affect the nervous system, resulting in paralysis and death. Explain the physical principles that trigger the production of nitrogen bubbles. How could you prevent this sickness? Justify all your responses

Doctors will prescribe multiple drugs in combination with levodopa for Parkinson’s disease (PD) . Describe: what these...

Doctors will prescribe multiple drugs in combination with levodopa for Parkinson’s disease (PD) . Describe: what these are and how they help to treat the symptoms of PD.

1. How has a market orientation contributed to Dollar Shave Club’s rapid growth? 2. Describe how...

1. How has a market orientation contributed to Dollar Shave Club’s rapid growth? 2. Describe how Dollar Shave Club embraces the marketing concept. 3. How is the marketing mix of Dollar Shave Club different from retail competitors like Gillette?

5.1 Combination and permutation a) 5C2 b) 5! c) Five different drugs, A, B, C, D,...

5.1 Combination and permutation a) 5C2 b) 5! c) Five different drugs, A, B, C, D, and E, can be used to treat a disease in different combinations. If a physician uses two of them to treat patients, how many combinations are possible? List all such combinations. d) Four different exercises, A, B, C, and D, are recommended for an injury recover therapy program. The therapists want to know whether there is a different treatment effect using i) just one;...

Question