Correlate the waves in an electrocardiogram with those of a cardiomyocyte action potential..

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Expert Solution

In an ECG , there are mainly 3 waves are prresent. They are P wave, QRS complex, T wave

The two main segments are P-R segment and S-T segment

P-R segment ( it is the segment between the end of the P wave and the starting of the QRS complex

S-T segment ( it is the segment between the end of the QRS complex and the beginning of the T wave

In the heart, electrical activity (depolarization and repolarization) proceeds in a sequential order

1)The start for a heart beat arises in the pacemaker cells of the sinoatrial (SA) node located in the right atria.because SA node is a autorhythmic node. From the SA node, the wave of depolarization moves through both atria, resulting in atrial contraction.This atrial contraction or depolarization is represented by the P wave in the ECG

2)The impulse then move through the intranodal pathway connecting the SA node with the atrioventricular node (AV node). At the AV node the impulse slows allowing the atria to contract before the ventricles depolarize.This is called AV nodal delay , it is represented by the P-R segment in the Ecg

The impulse then move from the AV node through specialized conducing tissue known as the Bundle of His. The Bundle of His branches (rightand left) within the septum that separates the ventricles and then into the Purkinje fiber system, which carry the impulse through the ventricular walls. This will produce ventricular contraction ( Ventricular depolarization ) . It is represented by the QRS complex

In ventricular contraction is due to the ventricular action potential

it has mainly 4 phases

The phase 0 is the ventricular depolarization , Here the depolarization is due to the opening of the Na + channel

Phase 1 - early repolarization stage is due to the efflux of the K+ ion through transient outward k+ channel

The phase 0 and phase 1 denote the QRS complex in the ECG

Phase 2 - plateau phase , it is due to the inward flux of the ca +ion and the outward efflux of the k+ ions . they are conteracting and the action potential remain un changed.

Phase 2 is represented by the S-t segment in the ECG

phase 3 - is the late repolarization phase , it is due to the outflux of the potassium ion through the inward rectifying k+ channel.

Phase 3 is represented by the T wave in the ECG

Sydney Mullin answered 1 year ago

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