Celebrex is a drug manufactured by Pfizer, Inc., used to relieve symptoms associated with osteoarthritis and...

Celebrex is a drug manufactured by Pfizer, Inc., used to relieve symptoms associated with osteoarthritis and rheumatoid arthritis in adults. In clinical trials of the medication, some subjects reported dizziness as a side effect. Researchers wanted to discover whether an association existed between the type of treatment and dizziness. The following table of counts is from data collected to answer this question of interest:

Drug

*Side effect*	Celebrex	Placebo	Naproxen	Diclofenac	*total*
Dizziness	83	32	36	5	156
No dizziness	4063	1832	1330	382	7607
Total	4146	1864	1366	387	7763

1. Calculate the expected cell count for Placebo group reporting dizziness if the null hypothesis is true. Show work. Only calculate this one cell’s expected count.

2. Calculate the following cell’s contribution to the chi-square statistic: Placebo reporting dizziness. Show all work. Only calculate this one cell’s contribution to the chi-square statistic. Report answer to four decimal places.

3. The following table lists the contribution to the chi-square statistic for all other cells. Using these values and your answer to #20, calculate the chi-square statistic. Report your answer to one decimal place.

Drug

Side effect	Celebrex	Placebo	Naproxen	Diclofenac
Dizziness	0.001		2.66	0.99
No dizziness	0.001	0.02	0.05	0.02

Χ² =

Expert Solution

orchestra answered 1 year ago

1. What is osteoarthritis? 2. What symptoms are associated with osteoarthritis? 3. How does osteoarthritis interact...

1. What is osteoarthritis? 2. What symptoms are associated with osteoarthritis? 3. How does osteoarthritis interact with age? 4. What is the pathophysiology of the articular cartilage during osteoarthritis? 5. What areas are most affected by osteoarthritis? 6 What is the treatment for Osteoarthritis? 6. What are the major patient teachings to assist the patient in living with osteoarthritis?

Demerol (meperidine) is a drug used to relieve moderate to severe pain through inhibition of the...

Demerol (meperidine) is a drug used to relieve moderate to severe pain through inhibition of the NADH dehydrogenase complex. Explain why this drug does not completely abolish oxidative phosphorylation.

Exercise 3.11 A new drug is being used to relieve the pain of arthritis. However, the...

Exercise 3.11 A new drug is being used to relieve the pain of arthritis. However, the drug may reduce a patient’s heartbeat too much. To investigate the drugs effect on a person’s heartbeat, different dosages of the drug were given to six patients, and 30 minutes later, the decrease in each patient’s heartbeat was recorded. Dosage X = (2.0, 1.5, 3.0, 2.5, 4.0, 3.0) measured in ml.?Decrease Y = (15, 20, 18, 16, 19, 17) measured in beat per minute...

Drug A is the usual treatment for depression in graduate students. Pfizer has a new drug,...

Drug A is the usual treatment for depression in graduate students. Pfizer has a new drug, Drug B, that it thinks may be more effective. You have been hired to design the test program. As part of your project briefing, you decide to explain the logic of statistical testing to the people who are going to be working for you. Write the research hypothesis and the null hypothesis. Then construct a table like the one below, displaying the outcomes that...

Two different pain reliever drugs, “Drug A” and “Drug B,” are developed to relieve arthritis pain....

Two different pain reliever drugs, “Drug A” and “Drug B,” are developed to relieve arthritis pain. A clinical study recruits 15 individuals with arthritis. The individuals are given each drug on different days and the number of hours of pain relief for each drug is recorded. This data is in the “arthritis.csv” data file. a) State the appropriate hypotheses to test if there is a difference in the hours of pain relief for Drug A versus Drug B, using “Drug...

Benadryl is an over-the-counter drug used to treat allergy symptoms. The formula of Benadryl is C17H21NO.How...

Benadryl is an over-the-counter drug used to treat allergy symptoms. The formula of Benadryl is C17H21NO.How many moles of C are present in 0.706 moles of Benadryl? Express your answer to three significant figures and include the appropriate units

Discuss at least three symptoms caused by physiologic changes and consequences of Gout and Osteoarthritis. Discuss...

Discuss at least three symptoms caused by physiologic changes and consequences of Gout and Osteoarthritis. Discuss the findings for each disorder, comparing and contrasting symptoms, lab findings, and possible etiologies. Discuss how pharmaceutical treatments are designed to alleviate those symptoms. What are the risks and benefits of these treatments? What are potential drug interactions with these medications?

1. How would eating polysaccharides relieve symptoms of feeling weak, lacking energy, and feeling thirty. The...

1. How would eating polysaccharides relieve symptoms of feeling weak, lacking energy, and feeling thirty. The patient went on a diet low in carbohydrates and calories and high in protein and fats. 2. Definite homeostasis and negative feedback. Explain significance of homeostasis in physiology and medicine using specific examples from the case of the patient in question 1.

Getwell Pharmaceutical Ltd. has developed a new medical product Y to relieve hay fever symptoms. Analysis...

Getwell Pharmaceutical Ltd. has developed a new medical product Y to relieve hay fever symptoms. Analysis of demand in 20 regional markets suggests the following demand function for the product Y: QY = 5680 – 20PY + 0.05Pop +1.5A + 0.4I where QY is market demand for product Y, PYis the price of Y, Pop is population, A is advertising expenditures ($), and I is average household disposable income ($). In a typical market, the unit price of Y is...

Flat affect and catatonia are symptoms most closely associated with

Flat affect and catatonia are symptoms most closely associated with 1. obsessive-compulsive disorder. 2. antisocial personality disorder. 3. schizophrenia. 4. bipolar disorder.

Question