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Pick a protein of interest.->insulin Use the Blast tool to find protein homologs of your protein...

Pick a protein of interest.->insulin

Use the Blast tool to find protein homologs of your protein and submit blast search.

Use the multalign tool to align five of the homologs and submit alignment.

Identify conserved amino acids and regions of homology.

Find a PDB for your protein or one of the homologs. If your protein has not been examined structurally. (Start Again)

Use Jmol to evaluate your proteins 3D structure and answer the following questions.

How many subunits in your protein?

Does your protein have any cofactors or coenzymes?

How many amino acids residues in one of the subunits of your protein?

How many amino acids interact at the interface of the subunits of your protein?

Does your protein have an active site or ligand binding domain and what are the key amino in that region.  

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Expert Solution

Following questions answered in step by step pictures below

Pick a protein of interest.->insulin

Use the Blast tool to find protein homologs of your protein and submit blast search.

Use the multalign tool to align five of the homologs and submit alignment.

Identify conserved amino acids and regions of homology.

Find a PDB for your protein or one of the homologs. If your protein has not been examined structurally

gladiator answered 1 year ago
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