The primary sequence of the peptide listed below. H2N -(1) - (2) - (3) - (4)...

The primary sequence of the peptide listed below.

H2N -(1) - (2) - (3) - (4) - COOH

H2N - Asp-Thr-Phe-Lys-COOH

H2N – D -T – F – K – COOH

Use the one letter amino acid code and identify from N-terminus to C-terminus.

a.Determine the pI of the peptide. (Round to 2 decimal points)

b. Would mutating residue #3 to Ala change the pI of the peptide? Explain.

c. Which type of noncovalent interaction would the indicated residue side chain make at the given pH? (H-bond, Hydrophobic or Van der Waals, or Ionic bond or Salt bridge)

Residue 1 @ pH 5.0

Residue 2 @ pH 6.0

Residue 3 @ pH 11.0

Residue 4 @ pH 10.0

d. Calculate the fraction of the peptides C-terminus protonated at pH 2.5 (Round to 2 decimal points)

Solutions

Expert Solution

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Consider a peptide with the sequence TEYR. 1.) Calculate the fraction of the peptide with all...

Consider a peptide with the sequence TEYR. 1.) Calculate the fraction of the peptide with all titratable groups protonated at pH 4. 2.) Calculate the pI of the peptide. Please show exactly how you come to your conclusion so I can understand how to properly do this. Thumbs up given to correct answers.

Returns on stocks X and Y are listed below: Period 1 2 3 4 5 6...

Returns on stocks X and Y are listed below: Period 1 2 3 4 5 6 7 Stock X 3% -2% 9% 6% -1% -4% 11% Stock Y 1% -4% 7% 12% 3% -2% -1% Consider a portfolio of 20% stock X and 80% stock Y. What is the (population) variance of portfolio returns? Please round your answer to six decimal places. Note that the correct answer will be evaluated based on the full-precision result you would obtain using Excel.

Returns on stocks X and Y are listed below: Period 1 2 3 4 5 6...

Returns on stocks X and Y are listed below: Period 1 2 3 4 5 6 7 Stock X 5% 6% -2% -4% 6% 10% 7% Stock Y 1% -3% 6% 3% 12% 7% -5% Consider a portfolio of 40% stock X and 60% stock Y. What is the (population) variance of portfolio returns? Please round your answer to six decimal places.

Returns on stocks X and Y are listed below: Period 1 2 3 4 5 6...

Returns on stock X are listed below: Period 1 2 3 4 5 6 7 Stock...

Returns on stock X are listed below: Period 1 2 3 4 5 6 7 Stock X 8% 0% 3% -2% 5% 12% 7% What is the (population) standard deviation of the data? Please specify your answer in decimal terms and round your answer to the nearest thousandth (e.g., enter 12.3 percent as 0.123). Note that the correct answer will be evaluated based on the full-precision result you would obtain using Excel.

Assume that there are a sequence of consecutive integers 1, 2, 3, 4, 5, ... 15....

Assume that there are a sequence of consecutive integers 1, 2, 3, 4, 5, ... 15. Tom and Jim respectively select a number from the sequence randomly (no repetition). Given that Tom’s number is divisible by 5, what’s the probability that Tom’s number is greater than Jim’s number ?

3. Two charges with fixed positions are listed below: q1 = −4 µC at (−2 mm,...

3. Two charges with fixed positions are listed below: q1 = −4 µC at (−2 mm, 2 mm); q2 = −14 µC at (3 mm, 2 mm). (a) (5 points) Determine the electric potential at the origin. (b) (10 points) If an α-particle were placed at the origin, determine the electric force on the α-particle due to the fixed charges. Note: an α-particle is a helium nucleus, which is made of two protons and two neutrons. (c) (10 points) Where...

1. What is a peptide bond? 2. How does the primary structure of proteins differ from...

1. What is a peptide bond? 2. How does the primary structure of proteins differ from the secondary structure? A. Peptide Bonds A.1 Structure of glycylserine Structure of serylglycine A.2 Hydrolysis of serylglycine Q.1 Why are heat and alcohol used to disinfect medical equipment? Q.2 Why is milk given to someone who accidentally ingests a heavy metal ion such as silver or mercury? Q.5 After working with HNO3, a student noticed that she had a yellow spot on her hand....

SE-FamilySize 1 1 4 3 2 4 2 3 4 2 4 1 4 2 2...

SE-FamilySize 1 1 4 3 2 4 2 3 4 2 4 1 4 2 2 4 5 4 5 4 4 2 4 3 1 2 3 5 5 5 Make a confidence interval. Be sure you show all the steps you took. Include a screen shot of any applet you used in your calculations. 2. Choose a confidence level (1 – α). 3. What is xbar? 4. What is s? 5. What is t? (Show a screen shot...

Below are the number of hours spent exercising: 2 3 4 4 4 5 1 1...

Below are the number of hours spent exercising: 2 3 4 4 4 5 1 1 4 4 4 1 2 3 3 2 Which descriptive statistics from your output would you NOT report for Hours spent Exercising? Why not? Write a few sentences describing the data (use APA formatting). This interpretation should not include only the numbers, but rather what the numbers tell you about the data. Create a histogram for the hours spent exercising. You can do this...

Subjects