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One of the genes that is commonly mutated in skin cancer is the gene that codes...

One of the genes that is commonly mutated in skin cancer is the gene that codes for the p53 protein. If both copies of the gene are mutated by UV light and the p53 protein is no longer functioning in a skin cell, the cell is not necessarily cancerous despite these mutations.   However, descendants of that cell are likely to develop into cancer.

Explain why having defective p53 proteins might lead to cells with many mutations present – a cancer-prone cell.

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