You are interested in the complete oxidation of glucose in a cell. If the pyruvate dehydrogenase...

You are interested in the complete oxidation of glucose in a cell. If the pyruvate dehydrogenase complex was inhibited, what product would you expect would be the first to accumulate in the cell?

Expert Solution

gladiator answered 1 year ago

1. What role does glucose oxidation play in the metabolism of an organism? 2. Pyruvate is...

1. What role does glucose oxidation play in the metabolism of an organism? 2. Pyruvate is referred to as the hub (central point) of glucose oxidation. Explain why. 3. Compare the efficiency of aerobic respiration and fermentation.

Which pathway reduces the most NAD+? 1. Glycolysis 2. Pyruvate Dehydrogenase Complex 3. Both Pyruvate Dehydrogenase...

Which pathway reduces the most NAD+? 1. Glycolysis 2. Pyruvate Dehydrogenase Complex 3. Both Pyruvate Dehydrogenase Complex & Glycolysis are the same as each other but greater than fermentation 4. Fermentation

why is pyruvate dehydrogenase the regulated enzyme of pdc but not dihydrolipoyl transacetylase or dihydrolipoyl dehydrogenase?...

why is pyruvate dehydrogenase the regulated enzyme of pdc but not dihydrolipoyl transacetylase or dihydrolipoyl dehydrogenase? what causes defective regulation of pdc? if cells have energy, it will not run PDC instead what will it run?

The conversion of pyruvate into acetyl CoA uses what enzyme? Pyruvate Hydrolase Pyruvate Carboxylase Lactate Dehydrogenase...

The conversion of pyruvate into acetyl CoA uses what enzyme? Pyruvate Hydrolase Pyruvate Carboxylase Lactate Dehydrogenase Citrate Synthase None of the above Jenny’s lungs have an intrapulmonic pressure of 762 mmHg and an intrapleural pressure of 757 mmHg. Atmospheric pressure is 759 mmHg. What is happening to Jenny? Jenny is inhaling Jenny’s ventilation is at a rest Jenny is exhaling Jenny is suffocating None of the above Which of the following enzymes does ubiquinone transport electrons to in the ETC?

Compare the Pyruvate Dehydrogenase Complex to the Branched Chain Ketoacid Dehydrogenase Complex. How are they similar...

Compare the Pyruvate Dehydrogenase Complex to the Branched Chain Ketoacid Dehydrogenase Complex. How are they similar and different in terms of functionality and nutrient requirements l. What organic acids are elevated when there is insufficient activity of the Pyruvate Dehydrogenase Complex (PDC) vs the Branched Chain Ketoacid Dehydrogenase Complex (BCKDC)? (Make sure to understand the difference between BKCDC and BCAA transaminase. These are two completely different enzymes in the BCAA degradation pathway) 1 point

Briefly explain the steps by which the pyruvate dehydrogenase complex converts pyruvate to acetyl CoA and...

Briefly explain the steps by which the pyruvate dehydrogenase complex converts pyruvate to acetyl CoA and deposits it in the mitochondrial matrix. What cofactors are used, what are the products formed? How is the complex activity regulated?

Pyruvate dehydrogenase complex catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, five cofactors...

Pyruvate dehydrogenase complex catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, five cofactors (a) thiamine pyrophosphate; (b) nicotine adenine dinucleotide (NAD+); (c) acetylCoA; (d) flavin adenine dinucleotide (FAD); and (e) lipoamide participate at various steps of the reaction. Explain the role of each cofactor in this reaction. You must use the chemical structures and electronic properties of the intermediates to justify your answers.

The pyruvate dehydrogenase complex catalyzes the reaction pyruvate → acetyl-CoA (Reaction 0 in the TCA cycle)....

The pyruvate dehydrogenase complex catalyzes the reaction pyruvate → acetyl-CoA (Reaction 0 in the TCA cycle). It is activated by AMP, CoA and NAD+, but it is inhibited by ATP, acetyl-CoA and NADH. What is the biochemical logic of this regulatory mechanism of the citric acid cycle? (In your response, be sure to address why specific molecules are activators and why specific molecules are inhibitors)

Write the overall reaction for pyruvate oxidation (for one pyruvate) Write the overall reaction for the...

Write the overall reaction for pyruvate oxidation (for one pyruvate) Write the overall reaction for the Citric Acid Cycle (for one acetyl-CoA) What was the overall reaction for glycolysis? Per glucose, how many pyruvate (and then acetyl-CoA) are formed? How many Citric Acid Cycles have to take place to break down the pyruvates from one glucose molecule? Write the overall reaction for pyruvate oxidation (for one glucose) Write the overall reaction for the Citric Acid Cycle (for one glucose) Using...

Which of the following coenzymes participate in the reactions of the pyruvate dehydrogenase complex?

Which of the following coenzymes participate in the reactions of the pyruvate dehydrogenase complex? 1) thiamine pyrophosphate 2) lipoic acid 3) FAD 4) NAD+ 5) CoA

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