In: Biology
linear quadratic curve fit yielded a value of beta < 0. explain under what circumstances this may be possible?
A linear quadratic equation describes the surviving cells after exposing to a radiation which is represented by:
S(D)=e−(D+ D2)
Where,
S(D) = cells survived after a dose (D) of the radiation is given.
= linear part of curve
= quadratic component.
From the equation it is clear that the the given dose and relative death of the cells increases in a squared manner.
So, When < 0 indicates that the survival of the cells is more than death when exposed to the dose of radiation.
The type of cell used or other factors may be the reason which includes damaged cells which has not undergone complete cell death after being exposed.