What type of bond would you expect to find associated with the primary structure of the...

What type of bond would you expect to find associated with the primary structure of the enzyme phosphofructokinase (PFK)? In your own words, describe the reaction involved in the formation of this bond including the molecular components as needed.

Solutions

Expert Solution

ans:)Phosphofructokinase (PFK) is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from ATP to fructose-6-phosphate to yield ADP and fructose-1,6-bisphosphate.

* Living organisms, both unicellular and multicellular, require energy to live and function. Energy is stored andprovided in the form of adenosine triphosphate (ATP).

* ATP is produced by multiple cellular processes including glycolysis, as well as aerobic and anaerobic respiration

* PFK is the most important regulatory enzyme of glycolysis. It irreversibly catalyzes the rate-limiting step ofglycolysis: the conversion of fructose -6-phosphate and ATP to fructose-1, 6-diphosphate and ADP.PFK exists as a homotetramer in bacteria and mammals.

* Each of the four monomers of PFK is composed oftwo similar domains. One domain has an ATP binding pocket. The other domain contains the substratebinding site and the allosteric site.

* An allosteric site is a regulatory binding site that affects enzyme activity andis distinct from the substrate-binding site of an enzyme. Various activators and inhibitors regulate PFK.Examples of PFK activators are ADP, AMP and fructose 2, 6 diphosphate. Examples of PFK inhibitors are ATPphosphoglycerate and citrate.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

What is the primary elements of a cash budget. Include what you would expect to find...

What is the primary elements of a cash budget. Include what you would expect to find on a cash budget and how a cash budget can assist in the management of cash for a business.

what type of interaction would you expect between the following groups in the tertiary structure? a.phenylalanine...

what type of interaction would you expect between the following groups in the tertiary structure? a.phenylalanine and isoleucine b. aspartate and histidene c.asparagine and tyrosin d.alaine and proline

List the type of correlation and casual relationship that you would expect to find for each...

List the type of correlation and casual relationship that you would expect to find for each of the following pairs of variables. a) the price of gasoline at the pump, the current world price of crude oil b) the fish population in a lake, the number of cottages around the lake c) the humidex rating (an index based on air temperature and humidity), the number of respiratory ailments reported d) the stock price of a telephone company, the cost of...

What drug treatment would you expect to administer for the pain associated with Myocardial Infarction?

Q1. What type of compensation would you expect in a patient with metabolic alkalosis? A.) A...

Q1. What type of compensation would you expect in a patient with metabolic alkalosis? A.) A compensatory respiratory acidosis caused by a decrease in respiratory rate. B.) A compensatory metabolic acidosis caused by an increase loss of bicarbonate in the urine C.) A compensatory alkalosis caused by an increased loss of H+ in the urine. D. A compensatory respiratory alkalosis caused by an increase in respiratory rate. Q2. Bicarbonate is reabsorbed into the epithelial cells of the proximal convoluted tubule...

If the coupon payment decreases, what would you expect to happen to bond prices? A) You...

If the coupon payment decreases, what would you expect to happen to bond prices? A) You would expect bond prices to increase because bond prices and interest rates are positively related. B) You would expect bond prices to fall since bond prices are the sum of the present values of the future payments associated with the bond. C) You would expect bond prices to increase because bond prices and interest rates are positively related. D) Bond prices will be unaffected,...

You would expect a bond of the U.S. government and a bond of an Eastern European...

You would expect a bond of the U.S. government and a bond of an Eastern European government to pay different interest rates because of differences in the bonds’ (Credit risk/ tax treatment/ term ). You would expect a bond that repays the principal in year 2040 to pay (the same/ higher/ lower ) interest rate as compared to a bond that repays the principal in year 2020. You would expect a bond from a software company you run in your...

Question