Question

In: Biology

Disease A is autosomal dominant. A total of 4% of the study population of 100 people...

Disease A is autosomal dominant. A total of 4% of the study population of 100 people are affected. How many carriers are in the study population?

Disease A is autosomal recessive. A total of 16% of the study population of 100 people are affected. How many carriers are in the study population?

TIA!

Solutions

Expert Solution

1. Disease is autosomal dominant so genotype of diseased individual will be( AA) or A2

Allele frequency of (A )=√4/100= 0.2

Assume this population to be Hardy weinberg equilibrium

Equation of hardy weinberg law = p+q =1  

or

p2 +q2 + 2pq =1

p is frequency of dominant allele and q is frequency of recessive allele let p= A and q is =a

So frequency of a is = 1-A

= 1-0.2

0.8

Frequency of hetergyotes is 2pq

2*0.8*0.2=  0.32

No of carrier in population are 0.32*100= 32

Ans. 32

2. Disease is dominant so genotype of diseased individual is AA (16%)

Allele frequency of A is = √16/100

= 4/10= 0.4

Allele frequency of a is 1- 0.4

= 0.6

Frequency of heterzygotes is 2*0.6*0.4

= 0.48

No of carrier will be 0.48*100= 48 ans.

gladiator answered 1 year ago
Next > < Previous

Related Solutions

If there is an affected heterozygous parent with Huntington’s disease (an autosomal dominant disease) who has...
If there is an affected heterozygous parent with Huntington’s disease (an autosomal dominant disease) who has children with an unaffected parent, what are the chances of them having kids with Huntington’s disease? If there are two parents who are heterozygous carriers for Cystic Fibrosis disease (an autosomal recessive disease) What are the chances of them having a child with Cystic Fibrosis disease?   What are the chances of them having a child who is a carrier for Cystic Fibrosis? What are...
Huntington disease is a rare neurodegenerative human disease determined by an autosomal dominant allele. (Because it...
Huntington disease is a rare neurodegenerative human disease determined by an autosomal dominant allele. (Because it is a rare disease, homozygous individuals are also rare.) The disorder is typically a late onset disease with symptoms appearing after the age of 30. A young man has learned that his father has developed the disease. What is the probability that the young man will also develop the disease? What is the probability that a child of the young man develops the disease?
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease that causes cysts in the...
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease that causes cysts in the kidneys that can lead to kidney failure. The most common gene mutated in this disease is PKD1. Imagine that you are researcher working on ADPKD and a doctor has provided you with biological samples from patient with ADPKD. You have been tasked with identifying the mutation in PKD1 and then to test how this mutation affects protein function. Use the links provided to research...
Huntington's Disease is caused by an autosomal dominant allele. Suppose a prospective father is diagnosed with...
Huntington's Disease is caused by an autosomal dominant allele. Suppose a prospective father is diagnosed with this disease. His own mother also had it, but not his father. The prospective mother has no family history of the disease. a. What are the genotypes of these two prospective parents? (Tell how many copies of the dominant Huntington's allele the man and the woman each has.) b. What is the probability that a child of theirs would inherit the disease? Explain.
More males are affected by a disease with this inheritance pattern A. autosomal dominant B. X-linked...
More males are affected by a disease with this inheritance pattern A. autosomal dominant B. X-linked recessive C. X-linked dominant D. Y-linked E. none of these
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles...
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles that control tongue length. The alleles are polymorphic in this population, with f(T1) = 0.95 and f(T2) = 0.05. Anteaters that have long tongues are T1T1, T1T2 individuals have medium-length tongues, and T2T2 individuals have short tongues. A disease that wipes out the ants with deep nests occurs in this ecosystem, exerting strong natural selection on the long-tongued anteaters (they are ineffective at eating...
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles...
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles that control tongue length. The alleles are polymorphic in this population, with f(T1) = 0.95 and f(T2) = 0.05. Anteaters that have long tongues are T1T1, T1T2 individuals have medium-length tongues, and T2T2 individuals have short tongues. A disease that wipes out the ants with deep nests occurs in this ecosystem, exerting strong natural selection on the long-tongued anteaters (they are ineffective at eating...
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles...
In a population of anteaters in South Africa, T1 and T2 are autosomal, incompletely dominant alleles that control tongue length. The alleles are polymorphic in this population, with f(T1) = 0.95 and f(T2) = 0.05. Anteaters that have long tongues are T1T1, T1T2 individuals have medium-length tongues, and T2T2 individuals have short tongues. A disease that wipes out the ants with deep nests occurs in this ecosystem, exerting strong natural selection on the long-tongued anteaters (they are ineffective at eating...
Sickle-cell anemia is an autosomal recessive disease, people with the disease have a ss genotype and...
Sickle-cell anemia is an autosomal recessive disease, people with the disease have a ss genotype and people without the disease have a SS genotype. People who have the disease get very ill, but people who have only one copy of the recessive gene are actually protected from getting malaria (Ss heterozygote genotype). Which area of the world is the frequency of sickle cell anemia the highest? Why do you think this is true (related to heterozygote advantage)? We talked about...
If 4% of a population has an autosomal recessive trait, what portion of the population are...
If 4% of a population has an autosomal recessive trait, what portion of the population are likely to be carriers? Assume that the population is large, and that the recessive trait doesn't affect fitness of the individual. List your answer as a percentage.
ADVERTISEMENT
Subjects
ADVERTISEMENT
Latest Questions
ADVERTISEMENT