Question

draw the complete mechanism for the formation of n methyl prozac oxalic acid salt from alcohol 2. do not forget to include formation of the salt.

Answer 1

The formation of N-methyl prozac oxalic acid salt required a two stage process.

1.

In which the first stage is two hour long and in that 3-dimethyl amino propiophenone is reduced with Sodium - borohydroxide and converted to 3- dimethyl amino-1-phenulpropanol.

2.

In the second stage of the formation of salt, which takes around 3 hour time, the previously made 3-dimethyl amino-1-phenylpropanol is mixed with p-chlorotrifluro methyl benzene in presence of potassium-butoxide to form the final product which is N-methyl Prozac and that is further isolated as a N-methyl prozac oxalate salt.

Hope this helps, this is step by step formation of NMP.