In: Statistics and Probability
A clinical trial was conducted to test the effectiveness of a drug used for treating insomnia in older subjects. After treatment with the drug, 23 subjects had a mean wake time of 96.9 min and a standard deviation of 40.9 min. Assume that the 23 sample values appear to be from a normally distributed population and construct a 95% confidence interval estimate of the standard deviation of the wake times for a population with the drug treatments. Does the result indicate whether the treatment is effective? Find the confidence interval estimate. min < o < min
Solution :
Given that,
s = 40.9
s2 = 1672.81
n = 23
Degrees of freedom = df = n - 1 = 23 - 1 = 22
At 95% confidence level the 
2 value is ,
= 1 - 95% = 1 - 0.95 = 0.05
/ 2 = 0.05 / 2 = 0.025
1 - 
 / 2 = 1 - 0.025 = 0.975
2L
= 
2
/2,df
=36.7807
2R
= 
21 - 
/2,df = 10.9823
The 95% confidence interval for 
 is,
(n
- 1)s2 / 
2
/2
< 
 < 
(n - 1)s2 / 
21 - 
/2
  
(22)1672.81
/36.7807< 
 < 
(22 )1672.81 / 10.9823
31.6319 < 
 < 57.8879
( 31.6319 , 57.8879 ) min