Question

In: Biology

Which of the following is not a situation in which a loss-of-function allele may be dominant...

Which of the following is not a situation in which a loss-of-function allele may be dominant to the wildtype allele?
a) the wildtype allele is haplosufficient
b) the wildtype allele is haploinsufficient
c) the loss-of-function protein forms a nonfunctional complex with the wildtype protein
d) the loss-of-function protein competes with the wildtype protein to bind a DNA target
e) the loss-of-function protein sequesters a substrate

Solutions

Expert Solution

Ans :- Option (a) the wild type allele is haplosufficient

A wild type allele is known as haploinsufficient when recessive to the loss of function allele.


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