In: Biology
Which of the following is not a situation in which a
loss-of-function allele may be dominant to the wildtype
allele?
a) the wildtype allele is haplosufficient
b) the wildtype allele is haploinsufficient
c) the loss-of-function protein forms a nonfunctional complex with
the wildtype protein
d) the loss-of-function protein competes with the wildtype protein
to bind a DNA target
e) the loss-of-function protein sequesters a substrate
Ans :- Option (a) the wild type allele is haplosufficient
A wild type allele is known as haploinsufficient when recessive to the loss of function allele.