What is the difference between statistically and clinically significant research

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A statistically significance in research is the relationship between 2 or more variables and its effects.A p - value of 5 % or lower is considered as statistical significant research study and if the p - value is large the research study is statistically insignificant. Statistical significance in research provides evidence about the plausibility of null hypothesis ,which hypothesizes that there is nothing more than random chance at work in data. Statistical significance is the ability to state that the observed difference in an outcome is not due to chance alone. Statistically significance . research is necessary for clinical significance but says nothing about the magnitude of effect.

Clinically significant research means the findings of the study is useful with patients. Clinical significance in research is the probabilities of benefit and harm .A clinical significant difference is clinically relevant and thus merits subsequent action.

Large sample + large effect = statistically significant and clinical significant

Large sample + small effect = statistically significant ,may not be clinically significant.

Small sample + large effect = maybe clinical significant but does not show statistically significance.

Nightingale answered 1 year ago

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What does the term statistically significant mean?

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