Question

Complete the required pharmacological information for the following medications: Percocet, Pepcid, Protonix, Reglan, Rocephin

1. Trade name: ___(Percocet)_____________________
2. Generic name: _________________________________
3. Classification of the drug: _______________________________________________________________________________________
4. Description of the drug and recommended doses (adults and children): _____________________________________________
5. Side effects: _____________________________________________________________________________________________
6. Contraindications: ________________________________________________________________________________________
7. Nursing considerations:_____________________

Answer 1

a)Percocet:

Generic name:OXYCODONE

Class: Analgesic,Opiod

Dose:

• Adult: 9mg/day orally for every 12 hours with food
• Pediatric:Dose adjustment for renal impairment-If a dose is less than 9mg is necessary use an alternate analgesic.

Side effects: Constipation, nausea, vomiting, Adrenal insufficiency,Respiratory depression,hypotension

Contraindication:

• Bronchial asthma
• Hypersentivity to oxycodone
• Respiratory depression
• Gastrointestinal obstruction

Nursing consideration:

• Instruct patient to report symptoms of respiration depression,adrenal insufficiency and serotonin syndrome.
• Advise patient to swallow sprinkle content on teaspoonful of soft food.Advise patient against sudden discontinuation of due that cause withdrawal symptoms.

b) Pepcid:

Generic name : Famotidine

Class: Gastric acid secretion inhibitor,Histamine 2 antagonist

Dose:

• Adult: 20mg orally twice or 40mg twice daily upto 12 weeks
• Pediatric : 1mg/kg/day orally divided twice daily or 40mg orally once daily at bedtime

Side effects: Constipation, Steven Johnson syndrome, angioedema, Rhabdomyolysis,seizures, Interstitial pneumonia.

Contraindication: History of hypersensitivity to other histamine antagonist, hypersentivity to famotidine.

Nursing consideration:

• Advise patient to take once daily at bedtime or twice daily at morning and before bedtime
• Tell patient that drug may be taken with antacid.
• Report signs of headache,dizziness,constipation

C) Protonix

Generic name: Pantoprazole

Class:Proton pump inhibitor

Dose:

Adult:20 to 40 mg once daily for 6 months

Pediatric:20mg orally once daily for 8 weeks.

Side effects: Atrophic gastritis, Steven Johnson syndrome, Rhabdomyolysis, Osteoporosis, Thrombocytopenia, Disorder of muscle

Contraindication: Bronchospasm,Urticaria, Angioedema, Acute interstitial nephritis

Nursing consideration:

• Warn patient to report diarrhea that does not improve especially watery stools,abdomina pain
• Tell patient to immediately repot of symptoms.
• Negative breath test 4 to 6 weeks after completion of therapy.

d)Reglan

Generic name: Metoclopramide

Class: Antiemetic,Dopamine antagonist

Dose:

Adult:10 to 20 mg Iv every 4 to 6 hrs

Pediatric:10mg Iv slowly over 1 to 2min as a single undiluted dose

Side effects: Body fluid retention,nausea,vomiting, asthenia, neuroleptic malignant syndrome.

Contraindication: Epilepsy, Pheochromocytoma, tardive dyskinesia, Gastrointestinal hemorrhage, Dystonic reaction,breast feeding women

Nursing considerations:

• Improvement in nausea and vomiting
• Hydration level Signs of extrapyramidal effects
• Advise patient to avoid concomitant use of tricyclic antidepressants.

e) Rocephin

Generic name:Ceftriaxone

Class: 3rd generation cephalosporin

Dose:

• Adult: 1 to 2 g IV/IM every 24 hrs
• Pediatric: 50mg/kg IM as a single dose

Side effects: Eosinophilic count raised, Erythema multiforme, Hemolytic anemia, Renal failure, Thrombocytosis, Kernicterus

Contraindication: Concurrent administration of calcium containing IV solutions, Hyperbilirubinemic neonates.

Nursing consideration:

• Monitor temperature,symptomatic improvement
• Monitor complete blood count
• Monitor Renal and hepatic function.
• Advise patient to report severe diarrhoea.