Which of the following statements about the movement of cargo along the axon of a neuron...

Which of the following statements about the movement of cargo along the axon of a neuron is TRUE?

		Microtubules within the axon support the unidirectional motion of materials from the cell body to the axon terminal, while materials transported back from the axon terminal to the cell body move along intermediate filaments.
		Movement toward the axon terminal is propelled by ATP hydrolysis while movement towards the cell body is propelled by GTP hydrolysis.
		Every dynein and kinesin can move their cargo in either direction relative to the axon terminal.
		Microtubules within an axon are arranged such that all microtubules point in the same direction with their minus ends toward the neuron’s cell body.

Solutions

Expert Solution

ANSWER :- c.) Every dynein and kinesin can move their cargo in either direction relative to the axon terminal.

Axonal transport /axoplasmic transport/ axoplasmic transport is a cellular process responsible for the movement of cargo like mitochondria, lipid, proteins etc, to form a neuron cell body, through the cytoplasm of its axon called the axoplasm.

Movement towards the cell body is retrograde transport and movement towards the synapse is called anterograde.

Dynein, a motor protein responsible for retrograde axonal transport , carries vesicles and other cellular products towards the cell bodies of neuron. It's light chain binds to cargo and it's it's globular head region bind the microtubules, along it.

Kinesin , also a motor protein walk towards the plus end of microtubule, transport cargo as anterograde axonal transport from the cell body to the axon tip.

Microtubules within the axon support the unidirectional motion of materials, from the cell body to the axon terminals, while materials ia transported back from the axon terminal to the cell body move not along the intermediate filaments.

Movement towards the axon terminal is propelled by ATP hydrolysis while movement towards the cell body is not propelled by GTP hydrolysis.

Microtubules withinn an axon are arranged such that all axonal microtubules are arranged with plus end directed away from the cell body.

gladiator answered 1 year ago

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