Question

You collect several thousand Drosophila melanogaster individuals from the UC Davis experimental orchard in Winters. Youuse1000 of these flies to establish a laboratory population, which you maintain at a census population size of 1000 each generation. You then establish from the remaining field-collected flies a series of replicated populations of size 10, 100, 200, and 500and maintain each at the starting size (10, 100, 200, 500) for several generations. After some time, you sequence each lab population.

a. If one plotted for each lab population, the frequency of each nucleotide variant vs. its true frequency in the UCD population, how would the correlations differ across lab populations?

b. Which lab populations do you think would provide the best estimate of the true UCD frequencies? Why?

c. Now imagine that one carried out the same type of correlation analysis of allele frequencies ,but instead of comparing each population to the true UCD frequencies you compare the allele frequency of the replicated populations to each other (e.g., the populations of size 10 are compared to one another, the populations of size 100 are compared to one another, etc.). How would the pairwise correlations of frequency vary from one population size to another?

d. What two aspects of the sampling of flies in this entire experiment would lead to allele frequency deviations from the true UCD frequencies for sites free of natural selection?

e. You measure sequence divergence between each lab population and the sibling species, Drosophila simulans. How will the expected divergence vary across replicated populations of different size? Why?

Answer 1

ANSWER :-

We collect several thousand Drosophila melanogaster individuals from the UC Davis experimental orchard in Winters.

We use 1000 of these flies to establish a laboratory population, which you maintain at a census population size of 1000 each generation.

You then establish from the remaining field-collected flies a series of replicated populations of size 10, 100, 200, and 500 and maintain each at the starting size (10, 100, 200, 500) for several generations.

a)Here, we need to find the correlations differ across lab populations

So,Recreate populace is one in which the quantity of people contrast and furthermore has certain measure of organic variety contrasted with unique examples.

On the off chance that the populace is shut ,, at that point the allele recurrence doesnot change over ages.

In the imitate populace which has variety in specific alleles , the varieties are profoundly communicated in reproduce populace.

b)Here we need to find Which lab populations would provide the best estimate of the true UCD frequencies

The populace with bigger populace number speaks to UCD populace .

Why because, the higher the populace number, the more assorted the populace . So also the assorted variety is of allelels is more in UCD .

So populace with 500 speaks to UCD .

c)Here, we need to find the pairwise correlations of frequency vary from one population size to another

In repeat populace , the variety is more contrasted with unique populace .

Between the repeat populace , single sort of variety will win in littler populace however more varieties will win in bigger populaces.

Along these lines, in the event that the populace shut, at that point the recurrence of allele will stay unaltered inside the populace.

Along these lines, in the populace with lesser people the recurrence of a specific alllele will be more and in bigger populace the recurrence of same allele will be less on the grounds that there are progressively various sorts of alleles in the populace

d) here we need to find What are the two aspects of the sampling of flies in this entire experiment would lead to allele frequency deviations from the true UCD frequencies for sites free of natural selection

Hereditary float and recombination assumes job in the populace separated from choice locales.

e) Here, we need to find How will the expected divergence vary across replicated populations of different size

In Small populaces (lab) will in general veer quick contrasted with enormous populace.

Why because, In populace with bigger number , the deviations will be available yet stay quiet in light of higher number of variety in alleles. In any case, in littler populace , the variety or deviations in alllele is higher and it is unmistakable on the grounds that the quantity of allleles will be less and can be before long reflected in the populace.

So populace with 10 will in general separate quick contrasted with populace with 200.

Thank you