Question

Typical anti-depressants create more of this neurotransmitter in the synapse to bind with postsynaptic neurons:

Answer 1

Antidepressants are drugs that are used to treat depression. They work by influencing three neurotransmitters:

1) Serotonin: It regulates appetite, sleep, memory, etc.

2) Norepinephrine: Involved in regulation of alertness, motor function, stress response

3) Dopamine: Dopamine is involved on decision-making, motivation, reward, etc.

The commonly prescribe antidepressants affect serotonin neurotransmission. Most commonly prescribed are SSRIs or selective serotonin reuptake inhibitors. They increase serotonin abruptly in the somatodendritic area of neurons releasing serotonin. This will cause somatodendritic serotonin-1A auto receptors to desensitize, increasing neuronal impulse.

The release of serotonin from axon terminal is increased causing postsynaptic serotonin receptors to desensitize. SSRIs inhibit the reuptake of serotonin at the synapse by the presynaptic neurons. As a result, serotonin remain in the synapse for a longer time. This will increase its concentration at the synapse for a longer time, resulting in increased action, especially in mood regulation. Serotonin antagonist and reuptake inhibitors (SARIs) inhibit serotonin reuptake as well as inhibit serotonin binding to its receptors on cells. This will allow serotonin to remain at the synapse for longer duration. Monoamine oxidase inhibitors will inhibit monoamine oxidase, an enzyme that breaks down serotonin, epinephrine and dopamine.

Right choice is serotonin.