Start transfer sequences in newly synthesized proteins are required for translocation of proteins into the nucleus...

Start transfer sequences in newly synthesized proteins are required for translocation of proteins into the nucleus across the NPC (T/F)

Expert Solution

Synthesis of proteins begins in cytosol.Newly synthesized proteins enters the endoplasmic reticulum(ER) and then it moves to Golgi apparatus and then secretory or lysosomal pathway.During translation these proteins enters the ER with a presence of a signal sequence that is hydrophobic with 20-30 amino acids which is located in N terminus.This signal sequence combines with Signal recognition particle or SRP to help protein pass through luminal surface of ER.The SRP stops any further translation process until this binding process.The proteins that needs to translocate to the nucleus needs additional sequences like start and stop transfer sequences.The start transfer sequence helps newly synthesized proteins to translocate through nucleus across the Nuclear pore complex(NPC).These sequences located internally and not in N terminus also can bind to the SRP and initiates translocation.But they are not cleaved after the translocation.Start transfer sequences in newly synthesized proteins are required for translocation of proteins into the nucleus across the NPC is a True statement.

gladiator answered 2 years ago

With respect to newly synthesized secreted proteins describe how they are sorted and transported through the...

With respect to newly synthesized secreted proteins describe how they are sorted and transported through the Golgi?

A newly synthesized protein generally folds up into a __________________ conformation.

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Explain where proteins are synthesized and then trace different routes taken by various types of proteins...

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Short segments of newly synthesized DNA are joined into a continuous strand by _____.

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The majority of proteins are imported into the peroxisome via translocation. What other mechanism do peroxisomes...

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Unlike carbohydrates, nucleus acids, and lipids, proteins have diverse functions in a cell. Proteins are polymers...

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question 16. Which of the proteins below are synthesized on the membrane bound ribosome of the...

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A scientist measured the properties of a newly synthesized gas molecule. At 55.00 degrees C and...

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