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Carbon dioxide has two important roles in the rubisco active site. What are these roles, and...

Carbon dioxide has two important roles in the rubisco active site. What are these roles, and how do they differ from each other

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Expert Solution

Ans . Rubisco ( Ribulose-1,5- bisphosphate carboxylase/oxygenase) is an enzyme involved in the first major step of carbon fixation, a process by which the atmospheric carbon dioxide is converted by plants and other photosynthetic organisms to energy - rich molecules such as glucose.

Rubisco is a dominant contributer to conversion of gaseous carbon dioxide into biomass.

Aerobic life forms, including heterotrophs, primarily derive their carbon through an autotrophic / photosynthetic route using CO2 as a carbon source. Rubisco accomplish this task by incorporating CO2 into a phospho-sugar, ribulose 1,5 -bisphosphate (RuBP). Incorporation of CO2 into RuBP generates two molecules of 3-phosphoglycerate. This simple compound is subsequently used to build other organic molecules of life.

Synthesized RuBisCO does not have a fully functional active site. It needs to be activated by a CO2 molecule that carbamylates its catalytic Lys to bind Mg2+ that completes the activation process.


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