Question

DIURETIC HOMEWORK

Check Yourself Pop Quiz  

Insert either TRUE or FALSE for each statement

1. __________ Diuretics can be divided into three major classes. Due to the inherent properties of this class, loop diuretics do not require potassium supplementation.

2. __________ Some examples of drugs known as “potassium-sparing” diuretics are triamterene, eplerenone, and spironolactone.

3. __________ When comparing all the classifications of diuretics, thiazide diuretics are the most likely to cause hyperkalemia and hypercalcemia.

4. __________ Drugs such as NSAIDS may be co-administered with “potassium sparing” diuretics without the risk of adverse consequences.

5. __________ Patients with a documented adverse reaction to sulfa drugs may not be able to safely receive loop diuretics.

6. __________ Aldosterone acts on the kidney to retain sodium and water and excrete potassium in the urine.   

7. __________ Thiazide diuretics have a much shorter duration of action than the other diuretic classes.

8. __________ Loop diuretics are the only class of diuretics that may cause ototoxicity.

9. __________ It is important to emphasize to the patient receiving spironolactone to eat potassium rich foods daily.

10. __________ Thiazide diuretics may increase total serum cholesterol.   

Answer 1

1. Diuretics can be divided into three major classes. Due to the inherent properties of this class, loop diuretics do not require potassium supplementation. - False

The statement is false as due to loop diuretics the apparent side effect is depletion or decrease in the potassium levels due to the increase in the secretion in the distal tubule. So the person taking this diuretics are required to take the potassium supplements to make up fot the loss due to urine

2. Some examples of drugs known as “potassium-sparing” diuretics are triamterene, eplerenone, and spironolactone - True

The statement is true as “potassium-sparing” diuretics work in the prevention of sodium re-absorption int he collection tubule by binding to the triamterene or by inhibition aldosterone receptors in case of eplerenone, and spironolactone

3. When comparing all the classifications of diuretics, thiazide diuretics are the most likely to cause hyperkalemia and hypercalcemia - True

The statement is true as thiazide diuretics have higher propensity to cause hyperkalemia and hypercalcemia by increasing calcium re-absorption by luminal membrane in case if Hypercalcemia and increasing sodium delivery in the distal tubule in the body in case of hyperkalemia. As compared to other diruretics like loop diuretics the thiazide are more potent and are the most likely to cause hyperkalemia and hypercalcemia

4. Drugs such as NSAIDS may be co-administered with “potassium sparing” diuretics without the risk of adverse consequences - False

The given statement is false as NSAIDS co-administered with “potassium sparing” diuretics can cause adverse risks and consequences such as chronic kidney related complications such as hyperkalemia, acute kidney failure, papilary necrocsis, etc.