A HIV positive patient of European ancestry has been referred to you for treatment. A standard treatment...

A HIV positive patient of European ancestry has been referred to you for treatment. A standard treatment is a cocktail of retroviral drugs including abacavir. Before prescribing this, you review the patient’s records and see that one of her cousins had a lethal reaction to abacavir treatment.

a. What test or tests would you do on the patient before starting her on abacavir?

b. What results of your test would cause you to not make this prescription

c. Explain to the patient, who is not a scientist, what tests you want to do and why you want to do these tests.

PLEASE BE SPECIFIC

Solutions

Expert Solution

Retroviral drug abacavir is a reverse transcriptase inhibitor used for the treatment of HIV infected patients but it may have lethal effect due to hypersensitivity reaction. it mediated by major histocompatibility complex class i (HLA B 5701)

a. to test the hypersensitivity skin patch test will be performed to test the associate hypersensitivity in the patient.

b. if the skin patch test give hypersensitive reaction then, the patient can not be prescribed with the abacavir. if, there is no sign of any kind of reactivity of hypersensitivity, then abacavir can be used for the retroviral treatment without any hesitation of lethality in the patient.

c. tell patient that when he was going through the reports associated to you, contains an statement that your cosine have some problem with abacavir drug, so before prescribing you the same drug, i wanted to be sure that you do not have any problem from that drug because genetics of your family may affect you also but not surly..

gladiator answered 1 year ago

Next > < Previous

Related Solutions

A patient has recently been diagnosed as positive for human immunodeficiency virus (HIV). The patient is...

A patient has recently been diagnosed as positive for human immunodeficiency virus (HIV). The patient is unsure whether the medication regimen prescribed is actually helping. The patient complains of several adverse effects and is especially upset because he or she was asymptomatic before beginning treatment. How would you respond? What information about the progression of HIV/AIDS could you provide that will aid the patient in sticking to the treatment regimen?

You have been notified that one of your softball players has been diagnosed as HIV positive...

You have been notified that one of your softball players has been diagnosed as HIV positive but are not told which athlete it is. You ask and are told that this information is confidential and that you should treat all athletes as if they are infected. 1. Discuss the pros and cons of this situation from the perspective of infection control. Your pitcher takes a line drive right in the face and is bleeding profusely. 2. Explain the steps you...

Your 36-year-old patient has just tested positive for HIV. He asks that you not inform his...

Your 36-year-old patient has just tested positive for HIV. He asks that you not inform his wife of the results and claims he is not ready to tell her yet. You also are aware that your sister has been seeing this man. What is your role legally? What would you say to your patient? Would you tell your sister?

Patience is 29 years old and has been HIV positive for 9 years. She has remained...

Patience is 29 years old and has been HIV positive for 9 years. She has remained asymptomatic and is not taking antiretroviral medication. Recently she was at the drop-in clinic to talk to a public health nurse about having a baby through artificial insemination. She said she had met a man who wanted to marry her and have children with her, but she was concerned about the baby contracting her HIV infection. Her latest blood tests indicated her CD4+ count...

Your patient has been undergoing outpatient treatment for leukemia and was hospitalized in the critical care...

Your patient has been undergoing outpatient treatment for leukemia and was hospitalized in the critical care unit last week with pneumonia and respiratory failure. His pneumonia was diagnosed as community-acquired MRSA. He was transferred to your oncology ﬂoor 2 days ago. Before you enter the room, you perform hand hygiene and don an isolation gown, gloves, and a mask. As you enter the room, your patient says, “Finally, someone comes in here. I feel like an alien, and you are...

Ms. Nicolette Nevin, age 26, has been diagnosed as HIV positive. She asks, “Do I have...

Ms. Nicolette Nevin, age 26, has been diagnosed as HIV positive. She asks, “Do I have AIDS, and am I going to die?” As her nurse, what should you say to her? When is the patient with HIV considered to have AIDS? Ms. Nicolette is started on a combination of Sulfamethoxazole and Trimethoprim (TMP- SMX [Bactrim, Septra, Cotrim]) medication. Why?

Explain how you would investigate an HIV drug resistant strain in an HIV infected patient.

Sauron is an HIV-positive patient who also suffers from herpes and rheumatoid arthritis. He was diagnosed...

Sauron is an HIV-positive patient who also suffers from herpes and rheumatoid arthritis. He was diagnosed with HIV in the late 90s and was prescribed a combination of three antiretroviral (ARV) drugs comprising two nucleotide reverse-transcriptase inhibitors (NRTI) and one non-nucleotide reverse-transcriptase inhibitor (NNRTI). Quite recently, his ARV treatment was changed to a fixed-dose combination (FDC) of the same drugs. His doctor also prescribed fluconazole as prophylaxis for candida suppression. a. If Sauron is taking interferon-α to treat the herpes,...

ase Scenario # 1 Your patient has been undergoing outpatient treatment for leukemia and was hospitalized...

ase Scenario # 1 Your patient has been undergoing outpatient treatment for leukemia and was hospitalized in the critical care unit last week with pneumonia and respiratory failure. His pneumonia was diagnosed as community-acquired MRSA. He was transferred to your oncology ﬂoor 2 days ago. Before you enter the room, you perform hand hygiene and don an isolation gown, gloves, and a mask. As you enter the room, your patient says, “Finally, someone comes in here. I feel like an...

Case Scenario # 1 Your patient has been undergoing outpatient treatment for leukemia and was hospitalized...

Case Scenario # 1 Your patient has been undergoing outpatient treatment for leukemia and was hospitalized in the critical care unit last week with pneumonia and respiratory failure. His pneumonia was diagnosed as community-acquired MRSA. He was transferred to your oncology ﬂoor 2 days ago. Before you enter the room, you perform hand hygiene and don an isolation gown, gloves, and a mask. As you enter the room, your patient says, “Finally, someone comes in here. I feel like an...

Subjects